epigenetics

Bipolar disorder (BD) is a severe and recurrent psychiatric disorder characterized by alternating manic, hypomanic, and depressive episodes, frequent comorbidity, high relapse rates, and an increased risk of suicide. Although the pathophysiology of BD remains incompletely understood, increasing evidence suggests that DNA methylation may represent an important epigenetic regulatory layer involved …

Nature Communications, Published online: 15 June 2026; doi:10.1038/s41467-026-73847-x Here the authors generate a new genome and the first embryonic methylomes of an Australian marsupial to show that the embryo retains high DNA methylation while the trophectoderm undergoes erasure, suggesting placental epigenetic reprogramming is ancestral to therians.

Background: Preterm infants requiring prolonged hospitalization in the neonatal intensive care unit (NICU) are often exposed to early-life stress, which may contribute to long-term health consequences. Epigenetic markers, particularly DNA methylation (DNAm) of stress-related genes such as SLC6A4 and NR3C1 , have been identified as potential biomarkers of early-life stress. Limited research has co…

A major mouse study found that some inherited traits are passed down through epigenetic changes that break the classic rules of genetics. Researchers discovered hundreds of cases where these chemical DNA marks behaved unexpectedly, including some that seemed to emerge out of nowhere. They also identified the first known naturally occurring paramutation in a mammal, hinting that environmental infl…

Author: Dr. Sameera Abuaish Affiliations: Basic Sciences Department, College of Medicine, Princess, Nourah bint Abdulrahman University Key themes: Neuroscience capacity building • Molecular and translational neuroscience • Epigenetics • Neuron–glia metabolic interactions • Neurogenetics of autism • Regional research development • International collaboration Reflection #1 Neuroscience research in …

Mahtab A Quddusi (noreply@blogger.com)
10/7/2025

Diet, pollution, stress and lifestyle choices influence DNA methylation—an epigenetic process that controls how your genes function and affect health. Ever wondered how your environment can shape your genes without changing your DNA code? That’s where DNA methylation comes in—a powerful biological switch that turns genes on or off. But what flips that switch? Everyday factors like diet, pollution…

Deborah Anifowose·...· Shinryo Isoda and Marielle Kothari
9/13/2025

Nutrition across the human lifespan has significant effects on health, not only through direct physiological pathways but also through epigenetic mechanisms that regulate gene expression without directly altering DNA sequences. This paper reviews how variations in micro- and macronutrient intake during critical developmental windows shape long-term health outcomes and disease risk in adulthood.

Statistical Approaches to Addressing Data Science Challenges in Epigenetic Aging Research Presented by Peter Song, Professor, Department of Statistics, School of Public Health, University of Michigan Wednesday, October 30, 2024, 4:00 PM, AUST 202 Webex Meeting Link Coffee will be served at 3:30 pm in the Noether Lounge (AUST 326) Abstract: DNA methylation (DNAm) has […]

This paper reveals that increasing awareness of the apparent effects of TEI is integral to improving public health policies. It demonstrates the need for future researchers to investigate how best to increase awareness of TEI for policymakers, healthcare professionals and the general public.

Huda Yahya Zoghbi, MD, the inaugural winner of the 2016 Mechthild Esser Nemmers Prize in Medical Science at Northwestern University, returned to Feinberg on Monday as part of the Simpson Querrey Institute for Epigenetics Distinguished Lecturer Series. The post Groundbreaking Geneticist Delivers Epigenetics Lecture appeared first on News Center .

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