neonatology

The No-POPPY study (NCT03396588), a double-blind, randomized trial compared morphine with clonidine therapy for neonatal opioid withdrawal syndrome (NOWS) and found that the duration of treatment was similar across groups. This is significant because perinatal use of morphine has the potential for neurodevelopmental consequences. Still, the clonidine group reached symptom stabilization (Finnegan …

Intellectual & Developmental Disabilities- Juniper Publishers Abstract Purpose: To determine whether an indication related to a decrease in hematocrit is predictive of an intracranial hemorrhage (ICH) on neonatal head ultrasound (HUS). Methods: This was a single center retrospective study of 215 neonatal head ultrasounds (HUS). The association between an ICH on HUS and indication related to hemat…

In the therapeutic hypothermia era, intracranial hemorrhage is increasingly detected in term and near-term neonates with hypoxic–ischemic encephalopathy (HIE), yet its clinical significance remains heterogeneous and is often oversimplified. This review uses a pattern-based approach for venous system–related intracranial hemorrhage in neonatal HIE, with particular emphasis on cerebral sinovenous t…

Background: Preterm infants requiring prolonged hospitalization in the neonatal intensive care unit (NICU) are often exposed to early-life stress, which may contribute to long-term health consequences. Epigenetic markers, particularly DNA methylation (DNAm) of stress-related genes such as SLC6A4 and NR3C1 , have been identified as potential biomarkers of early-life stress. Limited research has co…

BackgroundNeonatal hypoxic–ischemic encephalopathy (HIE) stands as a primary cause of neonatal brain injury, mortality, and long-term neurodevelopmental impairment, imposing a considerable burden on public health systems worldwide. Despite advances in clinical practice, accurate early diagnosis and reliable severity stratification of HIE remain formidable challenges when relying solely on convent…

FAU researchers are developing a new suctioning technique for ventilation in new born babies, “SMART-NEO” When babies are born weeks or even months too early, they often cannot breathe unassisted. To keep their lungs clear, mucous has to be cleared several times a day through the ventilation tube – a necessary but risky procedure. Researchers […]

Bijan Morshedi; Diego Maurente; Ursula Griffiths-Randolph; Elisabeth Kamano; Katharine Hopkins; Dana Baraki; Juliana Martins; Steven Warsof
3/4/2025

Author ORCID Identifier 0000-0001-6826-5337 (Morshedi) 0000-0002-9395-0907 (Griffiths-Randolph) 0000-0003-1980-5469 (Baraki) 0000-0003-1327-8979 (Martins) 0000-0002-1047-8003 (Warsof) DOI 10.25884/jam1-gp21 Document Type Original Research Subcategory Perinatology Abstract Background: The average rate of preterm birth in the US in 2021 was 10.1%. Although the rate of mortality from preterm birth h…

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