inflammatory-disease

PurposeRikkunshito, a traditional Japanese herbal medicine, is used to improve gastrointestinal (GI) function. However, its mechanisms of action in irritable bowel syndrome (IBS) remain unclear. This study aimed to investigate the effects of Rikkunshito on colonic pacemaker activity, inflammation, GI hormones, pain-related behaviors, and transient receptor potential (TRP) channel activity in a zy…

BackgroundKnee osteoarthritis (KOA) is characterized by the progressive degeneration of articular cartilage, necessitating novel therapeutic strategies to halt disease progression. Isoviolanthin, a natural flavonoid glycoside, has an unclear mechanism of action in KOA.MethodsWe employed network pharmacology and molecular docking, supported by in vitro assays, to investigate the mechanisms of isov…

The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that damages the connections between brain cells.

UCLA researchers have identified a population of dysfunctional immune cells -- dubbed "zombie macrophages" -- that accumulates in the liver during aging and fatty liver disease, driving the chronic inflammation behind both conditions.

Reginald McNulty’s Lab Explores Promising New Pathway for Treating Inflammatory Diseases

Irvine, Calif., May 15, 2025 — Inflammatory diseases such as arthritis, Alzheimer’s and even certain rare genetic disorders affect millions worldwide and often have few effective treatment options. A new […]

A study published in Nature looks at the inflammatory protein IL-11 and ageing in mice.    Prof Ilaria Bellantuono, Professor of Musculoskeletal … read more

Results of a large, prospective study published in The Journal of Nutrition suggest a potential benefit of fiber intake in Read More The post A need to re-evaluate dietary recommendations for management of inflammatory bowel disease appeared first on American Society for Nutrition .

A new study suggests that a unique set of regulatory networks controlled by neurons in the gut may be viable targets for future drug therapies to combat chronic inflammatory diseases including asthma, allergy and inflammatory bowel disease. Read the full story here.

Abstract The post Protective Effect of Mesenchymal Stem Cells Derived Secretome in an in Vitro Pro-Inflammatory Model of Intervertebral Discogenic Pain appeared first on Global Journals Publishing Group .

A team of Northwestern investigators has demonstrated that injection of anti-inflammatory peptide amphiphiles into intestinal lesions can reduce inflammation in an animal model of Crohn’s disease. The post Novel Injectable Therapy Shows Promise in Treating Crohn’s Disease appeared first on News Center .

JUNIPER PUBLISHERS-Advanced Research in Gastroenterology & Hepatology Pathology of Cardiovascular System in Patients with Inflammatory Bowel Diseases Authored by Khlynova OV* The purpose the work was studying of cardiovascular system disease prevalence and structure in persons with the inflammatory bowel diseases (IBD) using Gastroenterology department of the Perm regional hospital as an example.…