inflammatory-disease

Spinach, almonds, and sweet potatoes are celebrated as some of the healthiest foods on the planet. But for the millions of Americans living with inflammatory bowel disease (IBD), a new study from the UNC School of Medicine suggests that these same foods may be quietly worsening gut inflammation through a compound most people have never heard of.

Cardiovascular inflammation has been the talk of the town in cardiology, and while Novo Nordisk was wise to pursue treating it, results from the ZEUS trial have led to a thunderous debate on whether or not it ever played a role in ASCVD. To test the inflammatory hypothesis directly, ZEUS enrolled more than 6,300 patients […] The post ZEUS Tells Us Inflammation Might Not Be the Answer appeared fir…

ObjectiveThis study aimed to investigate the associations between serum inflammatory mediators and chronic pain after laparoscopic inguinal hernia repair in elderly patients.MethodsFrom March 2022 to June 2023, 116 elderly patients (≥65 years old) diagnosed with inguinal hernia were enrolled in this study. All patients underwent total extraperitoneal repair (TEP) by laparoscopic surgery. Blood sa…

IntroductionRheumatoid arthritis (RA) is a globally prevalent, chronic, systemic disorder of articular joints, with an auto-immune etiology, which eventually leads to physical disability. Peedanil Gold (PG), an Ayurvedic herbo-mineral medicine, has demonstrated anti-inflammatory activity in in vitro assays. Furthermore, it has also exhibited pharmacological effects in animal models of osteoarthri…

Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases.

Interleukin-17 receptor A (IL17RA) acts as a core mediator of pro-inflammatory signaling and contributes crucially to the pathogenesis of autoimmune disorders including psoriasis and rheumatoid arthritis. Monoclonal antibodies against IL17RA have achieved clinical application, yet their clinical utility is restricted by multiple drawbacks: high production cost, complicated manufacturing procedure…

Plasma exchange can help treat people with a rare inflammatory disease that can cause blindness, according to a systematic review and meta-analysis published on July 22, 2026, in Neurology(r), the medical journal of the American Academy of Neurology. Plasma exchange led to recovery for most people with the disease, which is called myelin oligodendrocyte glycoprotein antibody-associated disease (M…

Inflammatory bowel disease, often called IBD, is a group of long-term conditions that cause inflammation in the digestive tract. The two main forms are Crohn’s disease and ulcerative colitis. These conditions can cause symptoms such as abdominal pain, diarrhea, fatigue, weight loss, and reduced quality of life. While treatments have improved over the years, scientists […] The post Could Highly Pr…

PurposeRikkunshito, a traditional Japanese herbal medicine, is used to improve gastrointestinal (GI) function. However, its mechanisms of action in irritable bowel syndrome (IBS) remain unclear. This study aimed to investigate the effects of Rikkunshito on colonic pacemaker activity, inflammation, GI hormones, pain-related behaviors, and transient receptor potential (TRP) channel activity in a zy…

BackgroundKnee osteoarthritis (KOA) is characterized by the progressive degeneration of articular cartilage, necessitating novel therapeutic strategies to halt disease progression. Isoviolanthin, a natural flavonoid glycoside, has an unclear mechanism of action in KOA.MethodsWe employed network pharmacology and molecular docking, supported by in vitro assays, to investigate the mechanisms of isov…

The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that damages the connections between brain cells.

UCLA researchers have identified a population of dysfunctional immune cells -- dubbed "zombie macrophages" -- that accumulates in the liver during aging and fatty liver disease, driving the chronic inflammation behind both conditions.

Reginald McNulty’s Lab Explores Promising New Pathway for Treating Inflammatory Diseases

Irvine, Calif., May 15, 2025 — Inflammatory diseases such as arthritis, Alzheimer’s and even certain rare genetic disorders affect millions worldwide and often have few effective treatment options. A new […]

A study published in Nature looks at the inflammatory protein IL-11 and ageing in mice.    Prof Ilaria Bellantuono, Professor of Musculoskeletal … read more

Results of a large, prospective study published in The Journal of Nutrition suggest a potential benefit of fiber intake in Read More The post A need to re-evaluate dietary recommendations for management of inflammatory bowel disease appeared first on American Society for Nutrition .

Abstract The post Protective Effect of Mesenchymal Stem Cells Derived Secretome in an in Vitro Pro-Inflammatory Model of Intervertebral Discogenic Pain appeared first on Global Journals Publishing Group .