autoimmune-disorders

Interleukin-17 receptor A (IL17RA) acts as a core mediator of pro-inflammatory signaling and contributes crucially to the pathogenesis of autoimmune disorders including psoriasis and rheumatoid arthritis. Monoclonal antibodies against IL17RA have achieved clinical application, yet their clinical utility is restricted by multiple drawbacks: high production cost, complicated manufacturing procedure…

I was recently diagnosed with anti-NMDA receptor encephalitis. It is an autoimmune disorder where your body’s normally helpful antibodies start acting strangely. This leads to inflammation in the brain. This short blog briefly discusses some of my experience and prognosis. Target audience: Anyone relying on my work for their own projects. It all started with flu-like symptoms: heart racing, night…

Researchers are closer to understanding what drives the autoimmune disorder Sj gren's disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon. Their latest study finds that impaired regulatory T cells are a critical contributing factor to Sj gren's disease in both mice and humans, and identifies an existing rheumatology drug as a promising therap…