regenerative-medicine

Revolutionary devices, age rewinding, and cell regeneration: scientists are finding multiple promising approaches for curing blindness, and even for stopping vision loss before it starts.

Nasim Annabi, an associate professor of chemical and biomolecular engineering at the UCLA Samueli School of Engineering, has received two grants from the National Institutes of Health to support her research on developing regenerative biomaterials and bioadhesive therapies

A new treatment that blocks an aging-related protein restored lost cartilage in old mice and helped prevent arthritis after knee injuries. Human cartilage samples showed similar signs of regeneration, raising hopes for a future drug that could repair joints instead of replacing them.

Among the emerging applications of 3D printing in healthcare, regenerative soft tissue reconstruction has seen the least clinical progress and carries some of the highest unmet patient need. Every year, hundreds of thousands of women undergo lumpectomy, the surgical removal of a cancerous breast tumor, and the majority walk away cancer-free. What many also walk…

Experimental osteoarthritis therapies repaired damaged joints in animals and may enter clinical trials within 18 months. A new experimental treatment may one day allow arthritic joints to heal themselves — without major surgery. In animal studies, researchers successfully regenerated damaged cartilage and restored aging joints to a healthy state within just weeks. The breakthrough therapies [...]

For patients suffering from traumatic injuries that leave behind “volumetric” gaps — where significant bone and blood vessels are lost — the clock is always ticking. Without a nearby blood supply, cells in the center of a large injury cannot survive, often leading to permanent tissue loss or failed grafts. A team of eight scientists […] The post UT San Antonio researchers find ‘perfect recipe’ to…

Platelet-rich plasma or PRP is a regenerative product that has grown in popularity. The literature on clinical applications of PRP is all over the place. Whether it works or not for any particular application is unclear to me. Many orthopedists seem enthused about it. I haven’t seen any major adverse events linked to PRP. PRP […] The post Weekly reads: odd FDA PRP warning, H3.3 & CTCF, Iowa AG ge…

Wool-derived keratin membranes helped regenerate organized, stable bone tissue and may offer a promising alternative to collagen in regenerative medicine. A new study found that keratin, a structural protein taken from wool, can support bone regeneration in living animals. The material produced bone tissue that more closely matched healthy natural bone than collagen, which is [...]

This Collection highlights research on engineered allografts for regenerative medicine including engineered allografts, bioengineered grafts, decellularised scaffolds, tissue engineering, regenerative allografts, and composite tissue allotransplantation.

Extracellular vesicles in hydrogels allow cell-free therapy for intrauterine adhesions, including recovery of reproductive functions. The post Regenerative Gel Treats Female Infertility Caused by Intrauterine Adhesions appeared first on Advanced Science News .

Mechanically fine-tuning the microenvironment enables researchers to bioprint different types of musculoskeletal tissues. The post Novel bioprinting method lays the foundation for personalised regenerative medicine appeared first on Advanced Science News .

Parkinson’s disease is a long-term brain condition that affects movement, thinking, and daily life. It often develops slowly over many years. People with Parkinson’s may notice shaking, stiffness, slow movement, and trouble with balance. These symptoms happen because certain brain cells are damaged or lost over time. One of the key systems affected in Parkinson’s […] The post Scientists find way …

A cross-species study has identified key genes that govern regeneration, revealing a potential path toward inducing limb regrowth in humans. Scientists studying a shared gene in three very different animals, axolotls, mice, and zebrafish, have uncovered a possible path toward a future gene therapy that could help humans regrow lost limbs. The findings were published [...]

The heart is a pump that wears out over time—that, at least, was the prevailing view. New research has shown that the heart’s aging results from changes in intercellular communications, which tell heart cells, sometimes even healthy ones, to stiffen and break down. By decoding these complex messages, a team of researchers, led by Pinar […] The post Heart-on-a-chip device identifies youth-enhancin…

A lab-grown “mini spinal cord” just showed that futuristic “dancing molecules” might help heal paralysis. Researchers at Northwestern University have created the most sophisticated lab grown model of human spinal cord injury so far. In the new study, scientists worked with human spinal cord organoids grown from stem cells. These miniature, simplified versions of the [...]

Scientists reversed joint damage in mice by reprogramming aging cartilage cells.

A new study shows that engineered, cell-free cartilage can safely support bone regeneration without provoking immune rejection. New research suggests it may be possible to repair major bone damage using a tissue implant that contains no living cells. By relying on the body’s own repair machinery, the approach aims to encourage new bone growth while [...]

A Nature study reveals a small drug that helps adult neurons behave more like they did in early development—when growth was possible. In spinal cord injury models, it boosted nerve regeneration and improved hand function, pointing to a new repair strategy.

Even during the holidays, I keep looking over all the latest research and news on regenerative medicine, including recently related to a firm called Unlimited Bio. The umbrella term “regenerative medicine” includes gene therapies and gene editing. The field is seeing non-traditional trials of regenerative medicine-related technologies including genetic approaches for enhancement. Sometimes the sa…

Golden apple snails can regrow full, functional eyes. Studying their genes may reveal how to repair human eye injuries.