orthopedics

Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by progressive cartilage destruction, chronic inflammation, pain, and functional impairment. Conventional therapies primarily focus on symptom management and are unable to restore damaged articular cartilage or effectively modify disease progression. Consequently, increasing attention has been directed toward biologic an…

Back pain affects millions of people and can make everyday activities such as walking, sitting, working and sleeping difficult. New research suggests that changes in gene activity may help explain why the soft discs between the bones of the spine gradually become damaged and unusually hard. The study was carried out by researchers from the […] The post Scientists Find New Clues to Why Spinal Disc…

Mercy Medical Center's Institute for Foot and Ankle Reconstruction (IFAR) presents The Center for Orthopedic Innovation, a state-of-the-art research and education facility designed to accelerate orthopedic innovation, advance research, enhance physician education and support the development of next-generation foot and ankle implants and biologic therapies.

BackgroundDemand for arthroplasty due to osteoarthritis (OA) is rising with population aging and need for revision surgeries. Efforts to slow OA progression and prevent post-operative complications have been ineffective, likely due to inadequate identification of the primary disease-driving mechanisms underlying cartilage destruction. The aim of this study was to identify the primary disease-driv…

Hip pain is one of the most common reasons adults visit an orthopedic specialist. Many people immediately assume arthritis is responsible, but researchers from Yale University say that assumption can sometimes hide more dangerous problems. Their review, published in EFORT Open Reviews, describes three nonarthritic conditions that can quietly damage the hip and eventually destroy […] The post Thre…

With the support of National Institutes of Health funding, Johns Hopkins Medicine investigators, led by pathologist Aaron W. James, M.D., Ph.D., previously discovered that sensory neurons in skeletal tissue are constantly sensing their environment and are quick to respond to injuries. Now, through federally-supported research published today in Science Translational Medicine, they describe how th…

With the support of National Institutes of Health funding, Johns Hopkins Medicine investigators, led by pathologist Aaron W. James, M.D., Ph.D., previously discovered that sensory neurons in skeletal tissue are constantly sensing their environment and are quick to respond to injuries. Now, through federally-supported research published today in Science Translational Medicine, they describe how th…

Knee osteoarthritis affects ~16% of adults in the world and is considered one of the most incapacitating diseases. Despite the advances in scientific knowledge and biological treatments in the field of orthopedics, available nonsurgical treatments for knee osteoarthritis are limited and still ineffective in delaying or stopping the progression of arthritis. Biologics such as platelet-rich plasma,…

Osteoarthritis is the most common form of arthritis and affects millions of people worldwide. It develops when the protective cartilage that cushions the ends of bones gradually wears away. As the cartilage becomes thinner, bones rub against each other, causing pain, stiffness, swelling, and reduced movement that can make everyday activities difficult. Although treatments such […] The post Scient…

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