pain-management

For decades, one of the biggest problems in pain medicine has been surprisingly simple: the strongest medicines often come with the greatest risks. Opioids can make severe pain manageable, but they can also cause dependence, addiction, overdose and troublesome side effects. A new drug called LTG-001 is being developed to see whether powerful pain relief […] The post A New Way to Stop Pain Without…

Low back pain is something most people experience at some point in life. Long hours at a desk, repeated lifting, reduced activity and many other factors can contribute, but in most cases doctors cannot identify one specific injury or disease that explains the pain. This common form is called nonspecific low back pain. It accounts […] The post A Soft Back Belt May Ease Common Low Back Pain appeare…

IntroductionOsteoarthritis (OA) exhibits substantial heterogeneity in synovial immune profiles, which may underlie variable analgesic responses to standard biological and neuromodulatory treatments. Remodeling the immune microenvironment while targeting nociceptive pathways may improve therapeutic consistency.MethodsAnalgesic efficacy of platelet-rich plasma (PRP) combined with transient receptor…

A protein widely associated with cancer may have another surprising role in the human body: helping damaged nerves create long-lasting pain. New research suggests that blocking this protein could provide scientists with a new strategy for treating chronic nerve pain that does not respond well to existing medicines. The protein, called BRAF, was studied by […] The post An Unexpected Cause of Chron…

A seed-sized injectable device could make nerve stimulation therapies simpler, safer, and more accessible. Researchers at NYU Abu Dhabi, working with Cleveland Clinic Abu Dhabi, have created a tiny injectable device that could offer a less invasive way to treat chronic pain and movement disorders. The device is designed to control nerve activity without surgery, [...]

University of Texas M. D. Anderson Cancer Center
13d ago

A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often responds poorly to standard pain medications. Researchers at The University of Texas MD Anderson Cancer Center now report evidence that BRAF, [...]

A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often responds poorly to standard pain medications. Researchers at The University of Texas MD Anderson Cancer Center now report evidence that BRAF, […]

The University of Texas MD Anderson Cancer Center
18d ago

Researchers at The University of Texas MD Anderson Cancer Center found new evidence that BRAF, a protein commonly involved in cancer, plays a key role in developing, amplifying and maintaining chronic pain caused by nerve damage. Using BRAF inhibitors reduced pain sensitivity in preclinical models, suggesting the therapeutic potential of this approach for treating chronic nerve pain.

The University of Texas MD Anderson Cancer Center
18d ago

Researchers at The University of Texas MD Anderson Cancer Center found new evidence that BRAF, a protein commonly involved in cancer, plays a key role in developing, amplifying and maintaining chronic pain caused by nerve damage. Using BRAF inhibitors reduced pain sensitivity in preclinical models, suggesting the therapeutic potential of this approach for treating chronic nerve pain.

research.ioresearch.io

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