pain-management
For decades, one of the biggest problems in pain medicine has been surprisingly simple: the strongest medicines often come with the greatest risks. Opioids can make severe pain manageable, but they can also cause dependence, addiction, overdose and troublesome side effects. A new drug called LTG-001 is being developed to see whether powerful pain relief […] The post A New Way to Stop Pain Without…

Low back pain is something most people experience at some point in life. Long hours at a desk, repeated lifting, reduced activity and many other factors can contribute, but in most cases doctors cannot identify one specific injury or disease that explains the pain. This common form is called nonspecific low back pain. It accounts […] The post A Soft Back Belt May Ease Common Low Back Pain appeare…

A clinical trial led by Wake Forest University School of Medicine found that high-frequency spinal cord stimulation reduced pain and improved sensation in people with painful diabetic neuropathy.

A clinical trial led by Wake Forest University School of Medicine found that high-frequency spinal cord stimulation reduced pain and improved sensation in people with painful diabetic neuropathy.

Cluster headache causes extreme pain, but its origins remain unclear. New research links the disorder to genetics, inflammation, and tobacco smoke exposure. Unlike an ordinary headache, a cluster attack typically erupts without warning and causes excruciating pain around one eye. Episodes can last from 15 minutes to three hours and often return at similar times [...]
IntroductionOsteoarthritis (OA) exhibits substantial heterogeneity in synovial immune profiles, which may underlie variable analgesic responses to standard biological and neuromodulatory treatments. Remodeling the immune microenvironment while targeting nociceptive pathways may improve therapeutic consistency.MethodsAnalgesic efficacy of platelet-rich plasma (PRP) combined with transient receptor…
You probably don't think twice about putting on your socks – until your back makes...

A protein widely associated with cancer may have another surprising role in the human body: helping damaged nerves create long-lasting pain. New research suggests that blocking this protein could provide scientists with a new strategy for treating chronic nerve pain that does not respond well to existing medicines. The protein, called BRAF, was studied by […] The post An Unexpected Cause of Chron…
WEDNESDAY, Sept. 1, 2026 — Back braces have been used for decades to treat low back pain, but a new review has concluded that they don’t appear to help much.There’s little to no quality evidence available showing that back braces are effective in...

A seed-sized injectable device could make nerve stimulation therapies simpler, safer, and more accessible. Researchers at NYU Abu Dhabi, working with Cleveland Clinic Abu Dhabi, have created a tiny injectable device that could offer a less invasive way to treat chronic pain and movement disorders. The device is designed to control nerve activity without surgery, [...]

A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often responds poorly to standard pain medications. Researchers at The University of Texas MD Anderson Cancer Center now report evidence that BRAF, [...]

A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often responds poorly to standard pain medications. Researchers at The University of Texas MD Anderson Cancer Center now report evidence that BRAF, […]
A compound extracted from a hallucinogenic mint plant used in traditional Mexican medicine reduces facial nerve pain in mice. The findings reveal the biological mechanism behind the plant's historic use and highlight a potential target for future pain treatments.
Researchers discovered a brain-based “brake” that can shut down chronic nerve pain in mice by calming an overactive pain circuit. Targeting this system more precisely could one day lead to powerful pain relief without affecting opioid receptors throughout the entire body.

Researchers at The University of Texas MD Anderson Cancer Center found new evidence that BRAF, a protein commonly involved in cancer, plays a key role in developing, amplifying and maintaining chronic pain caused by nerve damage. Using BRAF inhibitors reduced pain sensitivity in preclinical models, suggesting the therapeutic potential of this approach for treating chronic nerve pain.

Researchers at The University of Texas MD Anderson Cancer Center found new evidence that BRAF, a protein commonly involved in cancer, plays a key role in developing, amplifying and maintaining chronic pain caused by nerve damage. Using BRAF inhibitors reduced pain sensitivity in preclinical models, suggesting the therapeutic potential of this approach for treating chronic nerve pain.

In this session: Kris Kruse-Elliott, DVM, PhD, DAVCAA, explores the principles of multimodal analgesia and how to apply them throughout the perianesthetic period in both canine and feline patients.

In this session: Kris Kruse-Elliott, DVM, PhD, DAVCAA, explores the principles of multimodal analgesia and how to apply them throughout the perianesthetic period in both canine and feline patients.

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