alzheimer-s

With a new model of the brain region essential to memory formation, from cells to whole-brain networks, the team hopes to identify critical changes in the progression of Alzheimer's disease that could point the way to earlier, more effective treatments.

Forty-Hz auditory stimulation increased amyloid clearance markers in aged primates and produced lasting effects, supporting its potential as a non-invasive Alzheimer’s therapy. Scientists at the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences have shown for the first time in non-human primates that sound stimulation at 40-Hz can significantly increase β-amyloid levels [...]

Blood tests that detect a protein involved in Alzheimer’s disease could help predict the age at which the disease may strike people long before they develop symptoms, according to a new study. But questions remain about the accuracy and uncertainty of these tests, and experts caution that the assays aren’t ready for prime time. “While the results here are encouraging, they are not yet at the leve…

Alzheimer’s disease changes everything for patients, their families, and the communities that support them. Yet even in the face of this devastating illness, there is hope through innovation, collaboration, and compassion. This conversation was inspired by Taking Care, a 38-minute documentary following the journey of acclaimed filmmakers Seth Rogen and Lauren Miller Rogen as they ...

A new Northwestern Medicine study suggests a promising alternative to current approaches to Alzheimer’s disease: enhancing the brain’s own immune cells to clear amyloid plaques more effectively. The post Alzheimer’s Treatment May Lie in the Brain’s Own Cleanup Crew appeared first on News Center .

A new mathematical model offers hope for better prediction and treatment of Alzheimer’s disease. Most mathematical models of Alzheimer’s are theoretical, focusing on short term molecular and cellular-level changes that cannot be measured in patients. However, researchers at Duke University School of Medicine and Pennsylvania State University have used real-world data from over 800 people with var…

Key Points Focused Ultrasound Mitigates Pathology and Improves Spatial Memory in Alzheimer’s Mice and Patients A collaborative research team of engineers and clinicians led by Elisa Konofagou, PhD, at Columbia University recently published results from their preclinical and clinical studies to determine whether opening the blood-brain barrier (BBB) with focused ultrasound can reduce brain plaques…

The UCI research team is developing the next generation of models that will be used to investigate Alzheimer's disease drugs, which are urgently needed, as more than 74 million people worldwide could be affected by 2030.

Dr. Monuki, Associate Professor of Developmental and Cell Biology and his graduate student Momoko Watanabe and colleagues have created a […]