dermatology

Adult genital psoriasis is associated with local symptoms and effects on sexual activity, intimate relationships, body exposure, and patient communication. The associated psychosexual burden is not adequately summarized by lesion severity or sexual function scores alone. This integrative review examines outcome measurement, construct coverage, and clinical recognition of psychosexual burden in ad…

Dermatophytosis is a superficial, highly contagious mycosis caused mainly by keratinophilic fungi of the genera Microsporum, Trichophyton and Nannizzia. This report describes two clinical cases of dermatophytic kerion in dogs caused by Microsporum canis. In both, direct microscopic examination of hairs revealed ectothrix arthroconidia, and fungal culture yielded colonies morphologically consisten…

Hair loss often is caused by a combination of heredity and aging, says Dr. Dawn Davis, a Mayo Clinic dermatologist. Treatments that may slow that type of hair loss and help regrow hair, including over-the-counter therapies such as shampoos, are available. And they can be effective.

Review addresses longstanding uncertainty around antihistamines for eczema Researchers advise against routine use and call for updated guidance  Adding oral antihistamines to existing eczema treatments is unlikely to lead to clinically important reductions in eczema and itch severity, and may not reduce sleep disturbance or flare-ups, finds a review of the latest trial evidence published by The .…

Nature Medicine, Published online: 23 July 2026; doi:10.1038/s41591-026-04534-z In a pair of pivotal phase 3, placebo-controlled, randomized clinical trials, the oral JAK1 inhibitor povorcitinib significantly reduced abscesses and inflammatory nodules in patients with moderate to severe hidradenitis suppurativa.

Therapeutic innovation has reshaped the dermatology landscape, expanding treatment options for chronic inflammatory dermatoses such as psoriasis, atopic dermatitis, vitiligo, chronic hand eczema, and hidradenitis suppurativa. Yet for many late-stage development programs, the central challenge is no longer whether a therapy can produce a short-term response. It is whether that response lasts, whet…

BackgroundPrurigo nodularis (PN) is a chronic neuroimmune skin disorder characterized by intensely pruritic nodules, severe impairment of quality of life and significant psychosocial burden. Prior to the approval of targeted therapies, management relied on conventional agents with limited efficacy. Recent evidence of its neuroimmune pathogenesis have led to the approvement of targeted biologics. …

Scientists have discovered a hidden warning sign of skin damage that appears before collagen fibers visibly thin, break, or lose their connections. Using advanced light-based techniques, the team found that collagen’s carefully organized molecular “handedness” can collapse even while the tissue still appears structurally intact and contains the same amount of collagen. This suggests that skin may…

IntroductionAcne vulgaris is a prevalent chronic inflammatory skin disease, and Cutibacterium overproliferation is a core pathogenic factor, yet findings remain controversial, partly due to single anatomical area sampling bias.MethodsWe conducted a crosssectional study with anatomically paired sampling across multiple facial anatomical areas in 85 subjects (30 healthy subjects, 55 acne subjects),…

Psoriasis is a persistent cutaneous disorder involving an imbalance in immune regulation, oxidative stress, and abnormal epidermal proliferation. This study evaluated the therapeutic efficacy of Ecballium elaterium (EE) balm compared with clobetasol propionate (0.05%) (CLO) in rats with psoriasis-like lesions induced by topical imiquimod (IMQ). A total of twenty-four adult male of the Wistar stra…

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