autoimmune-disease

In a new study published today in Science Advances, Northwestern Medicine researchers have uncovered a previously hidden immune environment in the thymus that may help drive myasthenia gravis (MG), a chronic autoimmune disease that causes muscle weakness and fatigue, mainly impacting women under age 40 and men over age 60.

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatme…

Often diagnosed in the teenage years, childhood-onset lupus is a serious, potentially fatal autoimmune disease that causes the body to attack itself. For as many as 10,000 U.S. youths, it can bring extreme fatigue, mood changes, pain and inflammation that affect many parts of the body. Now, these kids have an option for treatment that … The post Program for kids with lupus can change lives in 6 s…

Autoimmune diseases, where the body's own immune system mistakenly goes on the attack, are much...

Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammatory demyelination in the central nervous system, predominantly presenting in young adults, with a steadily increasing global incidence. In China, MS is classified as a rare disease and imposes a considerable medical and socioeconomic burden. Current clinical management mainly relies on immunomodulatory and immunosu…

CAR T cell therapy wipes out rogue antibodies' source and improves walking speed in people with the same autoimmune disorder that affects Celine Dion.

BackgroundPolycystic ovary syndrome (PCOS) is a common heterogeneous condition characterized by reproductive disturbances and significant metabolic and other comorbidities. Nevertheless, the interrelations between autoimmune disorders and PCOS are still not clarified. Therefore, the present study aims to investigate the specter of systemic and organ-specific autoimmune disorders in a large group …

Nicole Keepers is an expert on systemic lupus erythematosus ("lupus"). For years she has endured debilitating consequences of this autoimmune disease, which attacks tissues throughout the body, including the brain. While immunosuppressive and anti-inflammatory drugs lessen some of her symptoms, including fatigue, vasculitis (inflammation of the blood vessels), and abnormal heart rhythms, they do …

With support from The Pittsburgh Foundation, Dr. Sarah Gaffen research on Il-17 could led to new treatments for autoimmune disease.

New research by Swansea University and Cambridge University has revealed the causes and devastating impacts of delays – that can last decades - in diagnosing lupus, an auto-immune condition.

Viral infections may be involved in the pathogenesis of the lupus autoimmune disease. This was recently discovered by FAU researchers. Their research shows that messenger substances of the immune system trigger the disease when their production is not lowered after recovery from viral infection. The findings could open a new...

Tennis star Venus Williams withdrew from the US Open yesterday, citing difficulties with Sjögren’s syndrome, an autoimmune disease that affects about 4 million Americans. Like other autoimmune diseases, the immune cells of people with Sjögren’s attack the body, hitting the tear- and saliva-producing exocrine glands in particular. Thus, common symptoma of the syndrome are dry eyes and mouths — but…