Organic Chemistry

Research Summary The research conducted in my group is focused on the reactions between transition metal complexes and simple molecules, particularly hydrocarbons and N2. Our work generally involves a mechanism-based approach to the development of catalysts. Catalytic functionalization of C-H bonds The catalytic functionalization of alkanes and other molecules with normally inert C-H bonds is a s…

Research There is worldwide interest in developing sustainable electrochemical methods for producing fuels and other chemicals that are currently derived from coal, oil, and natural gas. Research in the Lipke Lab contributes to these efforts by examining fundamental chemical questions regarding the mutual interactions of electrons, molecules, and materials. Our studies employ a bottom-up experime…

Research Summary We study molecular structure and reactivity. Our goal is to bring new reactions into the arena of synthetic organic chemistry and to develop superior synthetic strategies. For each reaction a mechanistic framework is established. The transformation is then developed into a preparative method and applied to specific targets, such as to the synthesis of molecules that pose practica…

RESEARCH SUMMARY The primary research interest of our group is to develop and integrate nanotechnology and chemical biology to modulate signaling pathways in cancer and stem cells. More specifically, our research focuses on identifying the various microenvironmental cues (e.g. soluble signals, cell-cell interactions, and insoluble/physical signals) affecting stem cell and cancer cell fate and the…

Research Summary Our group combines experimental and computational methods to understand mechanisms of reactions important for chemistry and biology. Specifically, we utilize traditionally physical methods, primarily mass spectrometry and computational chemistry, to tackle problems at the chemistry/biology interface, focusing on catalysis. We work on both biological catalysis, uncovering the mech…

Research Summary Heinz D. Roth and his group are interested in organic reaction mechanisms and elucidate structure and reactivity of short-lived free radicals or radical ions in solution or solid matrices. The structures are characterized by optical methods (including diffuse reflectance, DR), magnetic resonance techniques (electron spin resonance, EPR, or chemically induced dynamic nuclear polar…

Research Summary Host-Guest Chemistry; Supramolecular Chemistry; Design and Synthesis of Molecular Containers; Inner Phase Chemistry and Catalysis; Reactive Intermediates; Strained Hydrocarbons; De Novo Design of Helical Peptides; Conformationally Constrained Amino Acids; Peptide-based Ion-Channels; Photochemical Triggers for Protein Folding Host-Guest isolation of reactive intermediates: 1,2,4,6…

Research Summary My research interests are in natural products synthesis and the development of new synthetic methodology. Total synthesis of antitumor natural products and their analogs We are working on the total synthesis of the natural products, FR900482 and mitomycin C. These compounds are of interest to medicinal chemists because of their potent antitumor properties. We also synthesize anal…

Enver Cagri Izgu obtained a B.Sc. degree in chemistry from the Middle East Technical University (METU) in Turkiye, where he studied asymmetric organic catalysis with Ozdemir Dogan. Dr. Izgu then earned his Ph.D. in organic chemistry from the University of Minnesota under the tutelage of Thomas Hoye. During graduate research, he conducted the total synthesis of structurally complex and biologicall…

Research Precise structural control is critical for nanoscale designers to harness the optical, electrical, magnetic, chemical and biological properties of nanomaterials and nanomedicines. Our research will focus on applying organic and polymer chemistry to construct bottom-up assemblies of metal ions, clusters and inorganic nanoparticles. We aim to develop systemic designs for functional group b…

Research Summary My research interests are in synthetic organic chemistry, including the development of new synthetic methods and the synthesis of natural products. Over the last 45 (https://research.rutgers.edu/news/rutgers-chemist-named-2022-american-chemical-society-fellow) years we have developed methods for the stereoselective functionalization of alkenes, the construction of a variety of ni…

Research Summary My main area of interest is in chemical education, with a focus on textbooks. I have written several textbooks for General Chemistry and Allied Health Chemistry and am currently preparing an Organic Chemistry text. The thrust of my efforts in this area is the development of techniques for presenting the concepts, theory, and applications of chemistry to beginning students, and fo…

Research Interests The primary research activities in my group focus on the design, synthesis, and self-assembly of novel inorganic and organic-inorganic hybrid nanostructured and nanoporous materials and nanobiomaterials having unique catalytic, surface, biological, and electronic properties. Our materials are typically chosen to have multifunctional groups as well as novel structures at the nan…