Jimenez, Leslie

Research Summary My research interests are in natural products synthesis and the development of new synthetic methodology. Total synthesis of antitumor natural products and their analogs We are working on the total synthesis of the natural products, FR900482 and mitomycin C. These compounds are of interest to medicinal chemists because of their potent antitumor properties. We also synthesize analogs of these molecules to probe their biological mechanisms in an effort to develop a better...