pulmonology

ObjectiveGiven the high prevalence and clinical significance of insomnia in COPD patients, and the ongoing controversy surrounding benzodiazepine receptor positive allosteric modulators (PAMs) therapy, this study systematically evaluates the dual-temporal (short- and long-term) safety profile of PAMs through simultaneous assessment of therapeutic benefits and multidimensional risks in COPD-insomn…

A new study from researchers at National Jewish Health and collaborating institutions has found that different patterns seen on lung scans can signal how severe sarcoidosis may be, and how it affects breathing.

As people grow older, it is normal for the body to change in many ways. Muscles may become weaker, bones may lose strength, and the lungs may not work as well as they once did. However, new research suggests that obesity may add an extra burden on lung health in older adults, beyond what would […] The post Obesity decreases lung function in older people appeared first on Knowridge Science Report .

IntroductionAcute lung inflammation has recently gained increasing attention due to the high acute respiratory distress syndrome complications with subsequent fibrosis during the COVID-19 pandemic. Our group identified that the antifibrotic effect of the antidepressant fluvoxamine (FLU) in various organs is meditated via sigma-1 receptor (S1R) agonism. Since the actions of FLU on the inflammatory…

BackgroundsType 2 asthma is characterized by airway inflammation, mucus hypersecretion, and remodeling, and circadian rhythm dysregulation is implicated in its pathogenesis. Melatonin, a key circadian hormone, modulates inflammatory signaling, but its role in type 2 airway inflammation remains unclear. This study investigated whether melatonin alleviates airway inflammation and epithelial-mesench…

Next step Choose the next useful decision step first. Use the guide or checklist that matches this page's intent before you ask for a manuscript-level diagnostic. Quick answer: Pulmonology covers a wide range of conditions and research types: asthma, COPD, interstitial lung disease, pulmonary hypertension, lung cancer screening, respiratory infections, sleep medicine, and critical care. The journ…

Bronchoscopy in ventilated patients severely narrows the endotracheal tube lumen and increases resistance, which can lead to hypoventilation and intrinsic PEEP build-up. These ventilation impairments depend on the geometry of the tube-bronchoscope combination, ventilator settings, and patient mechanics. Currently, no predictive method exists to quantify these impairments or guide compensatory...

When it comes to keeping patients breathing comfortably, few specialties are as vital as pulmonology. Pulmonologists serve as the medical detectives of the respiratory system, diagnosing and treating conditions ranging from asthma to more complex illnesses such as lung cancer. Often on the frontlines in the ICU, when patients are struggling to breathe, their role is both challenging and deeply im…

A new Northwestern Medicine study is challenging long-held assumptions about chronic obstructive pulmonary disease (COPD), according to results published in The Journal of Clinical Investigation. The post Carbon Dioxide May Drive Lung Damage in COPD appeared first on News Center .

A new study led by Dr. Frank Sciurba, published in The New England Journal of Medicine, reveals that mepolizumab can significantly reduce exacerbations in COPD patients with eosinophilic inflammation—affecting up to 40% of those with the disease.

Better suppresses usual nocturnal worsening of asthma than dosing at other times May lead to better outcomes without increasing steroid-related side effects or costs A single daily preventer dose of inhaled corticosteroid (beclomethasone), taken mid afternoon, may be the best timing for effective asthma control as it suppresses the usual nocturnal worsening of symptoms more ...

Pulmonary & Respiratory Sciences - Juniper Publishers Abstract Idiopathic Pulmonary Fibrosis (IPF) presents a complex challenge in respiratory medicine, characterized by insidious onset and relentless progression. This comprehensive analysis delves into predictive biomarkers across diverse domains to enhance early detection, precise patient stratification, and personalized therapeutic interventio…

At Dr. Kartik Bhosale Cardiology Clinic, we are dedicated to providing top-notch chest care services under the expert guidance of Dr. Dnyandeep Sarpe, a distinguished chest physician, and pulmonologist. With a profound commitment to your respiratory well-being, we offer a comprehensive range of specialized services tailored to address various chest-related concerns. At Dr. Kartik Bhosale Cardiolo…

Pulmonary & Respiratory Sciences - Juniper Publishers Introduction Substance abuse is one of the major concerns in the world today as millions of people are abusing legal and illegal drugs for recreational purposes. Pulmonary complications of intravenous (IV) drug abuse include infections, airway and interstitial disease, respiratory failure, pulmonary edema, and the acquired immunodeficiency…

E-Cigarettes: Risk Assessment and Possible uses for  Patients with Severe COPD - An Update by Thomas Hering in GJARM - Juniper Publishers Taking market data as a basis, e-cigarettes continue to enjoy major success [1]. Topulmonologists it falls to assess this development, to advise patients adequately and if appropriate to support their use. Even though for long-term risk assessment the state …

Emphysema is a long-term and devastating lung disease. As it progresses, the body’s own inflammatory enzymes slowly digest and destroy alveoli, the delicate sacs where oxygen from air is transferred to the bloodstream. The damaged alveoli form large holes in lung tissue that impair gas exchange in the rest of the organ, leading to shortness of breath, wheezing, chronic cough, and, eventually, dea…

Acute and chronic airways diseases represent a large proportion of the inpatient and outpatient population continuously under the care of pulmonary physicians and primary healthcare providers. This review article aims […]

This year marks the 50th anniversary of the US Surgeon General’s first ever report, which implicated smoking as the primary cause of emphysema and other chronic diseases. Despite decades of research, emphysema—a form of chronic obstructive pulmonary disease (COPD), which ranks among the third leading cause of death in the US—remains incurable. Read more Continue reading →

Chronic obstructive pulmonary disease (COPD) is caused by emphysema and chronic bronchitis that damages the airways of the lungs leading to significantly reduced air flow and is predicted to be the third largest cause of death by 2030. Symptomatic relief is given by prescribing up to three different drugs for concurrent use, but the complexity […]