autoimmune-diseases

Rituximab, a chimeric anti-CD20 monoclonal antibody, is widely used to treat autoimmune diseases and hematologic malignancies through B-cell depletion, yet paradoxical autoimmune phenomena, including drug-induced lupus erythematosus, have been increasingly recognized. While paradoxical autoimmune phenomena following rituximab therapy have been reported, drug-induced subacute cutaneous lupus eryth…

Her immune system was already implicated in diseases affecting her liver, bile ducts, and large...

Evotec SE announced that it has entered a strategic R&D collaboration with Odyssey Therapeutics, Inc. to discover potential new treatments in autoimmune and inflammatory diseases. Under the agreement, Odyssey will leverage Evotec's integrated data-driven discovery platform, advanced screening capabi...

Findings from Bonn, Edinburgh and Newcastle could give a boost to pharmaceutical research.

Systemic lupus erythematosus (SLE), often called lupus, is a long-term autoimmune disease in which the immune system mistakenly attacks healthy tissues. Lupus can affect many parts of the body, including the skin, joints, heart, lungs, brain, and kidneys. One of the most serious complications is lupus nephritis, a condition in which the kidneys become inflamed […] The post Lupus Patients May Face…

Scientists have made an important discovery that may help explain why some people develop both leukemia and autoimmune diseases. The research was carried out by scientists at the Garvan Institute of Medical Research in Australia. Their findings could eventually lead to better ways to diagnose, treat, and even prevent these serious illnesses. Leukemia is a […] The post Scientists Find Common Trigg…

Systemic sclerosis is a rare connective tissue disorder characterised by autoimmune features with vascular manifestations, causing fibrosis of the skin and internal organs.

Knowing that women are diagnosed with multiple sclerosis (MS) at three times the rate of men, particularly during their 30s and 40s, scientists in the CU Anschutz lab of Kimberley Bruce , PhD, recently took that window of opportunity and ran with it.

A patient with three different autoimmune diseases has entered complete remission after undergoing an experimental...

For a long time, treatments for autoimmune diseases could only quash the symptoms - now new drugs may tackle the underlying cause

Taking a playful approach to raising awareness of serious diseases and opening up new channels for patient communication: the app “Fighting Lupus” developed by Sandra Jeleazcov and Benedikt Morschheuser. “Imagine a girl: young, lively, incredibly talented. Suddenly she becomes ill: LUPUS, a cute name, but a brutal autoimmune disease.” These are the opening words in […]

In a study out today, Duke researchers describe a newly discovered interaction of two specialized cells in the protective covering of the brain (dura). This interaction—between mural cells and macrophages— controls the movement of immune cells that target the central nervous system (CNS) and may be important in driving CNS autoimmune diseases like multiple sclerosis. “The immune system and the CN…

Learn about SLE symptoms, causes, diagnosis, and effective management strategies for living well with systemic lupus erythematosus. The post Systemic Lupus Erythematosus (SLE): Understanding Symptoms, Causes, Diagnosis and Management appeared first on THE SCIENCE NOTES .

Nathalie Conrad recently completed a research project, which shows that patients with autoimmune disorders live with an increased risk of developing cardiovascular disease. The scientist from KU Leuven will participate in #LINO23. Der Beitrag Young Scientists at #LINO23 – Autoimmune Diseases and Cardiovascular Risk erschien zuerst auf Lindau Nobel Laureate Meetings .

Autoimmune diseases affect millions of people, and have become an important focus of scientific research in the past decade due to their apparent increase in prevalence worldwide [1][2] - and yet little is known about their cause. Our body’s immune system is a pathogen-fighting machine, finely adapted to seek and destroy any foreign invaders which might cause damage within our bodies. To do this,…

Scientists found mice predisposed to diabetes were more likely to develop the disease if exposed to a virus. Diabetes, lupus, multiple sclerosis and rheumatoid arthritis are examples of diseases where the body’s immune system mistakenly attacks healthy tissue. Researchers believe the body may act correctly to repel an invading virus but then extend its attack to molecules similar to those in the …