Biologic therapies targeting IL-5 or its receptor reduce eosinophilia and exacerbations in asthma. Breakthrough eosinophilic attacks are usually considered biologic failure. We report 2 patients with severe asthma receiving mepolizumab or benralizumab who developed relapsing hypereosinophilia associated with Pseudomonas aeruginosa airway infection. Case 1 was a 71-year-old woman in Canada with se…
American College of Allergy·Asthma and Immunology (ACAAI)
25d ago
Being ready for the school year means more than gathering clothes and supplies - it also means adequately preparing your child and the school staff to deal with your child's allergies and asthma.
Bedfont® Scientific Limited, an innovative leader in breath analysis and Fractional exhaled Nitric Oxide (FeNO) testing for asthma care with the NObreath®, welcomes the news that over 1 million people with asthma are now using combination inhalers following the joint 2024 asthma guidelines from the National Institute for Care Excellence (NICE), the British Thoracic Society (BTS), and the Scottish…
A growing body of research suggests that good nutrition does more than support general health. It may also play an important role in keeping the lungs healthy, especially for people living with asthma. A new study published in the journal Thorax has found that higher blood levels of vitamins A and D are linked to […] The post Higher Vitamin Levels Linked to Healthier Lungs and Slower Aging in Peo…
BackgroundThe role of oral bacterial lysates (OBLs) as adjuvant immunomodulatory therapy in pediatric asthma requires clarification. This systematic review and meta-analysis evaluates their efficacy and safety.MethodsWe searched eight databases for randomized controlled trials (RCTs) in children comparing standard asthma therapy plus OBLs versus standard therapy/placebo. Primary outcomes were cli…
New research presented at this year's European Congress on Obesity in Istanbul, Turkey (12-15 May) shows the use of the new GLP-1 class of obesity drugs in people with asthma is associated with a 26 % fall in the number of asthma exacerbations and a 14% drop in use of asthma inhaler reliever use. The study is by Simon Høj and Dr Kjell Erik Julius Håkansson, Copenhagen University Hospital, Copenha…
Paediatric asthma is a chronic inflammatory airway disease that can cause airway swelling, excessive mucus secretion, and increased smooth muscle tone, leading to airway narrowing and respiratory distress. Airway remodelling involves a series of pathophysiological alterations, including airway epithelial injury, proliferation of mucous glands and goblet cells, subepithelial fibrosis, proliferatio…
New industry support enables the team to expand their search and validation of diagnostic biomarkers to shed light on asthma with thus far unexplained causes and improve therapy
