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The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. David Chou’s work is literally out of this world! In addition to identifying radiation countermeasures for use on Earth, he is part of the AVATAR project, which aims to understand how humans… S…

A conversation with Matthew Woodworth about mental health awareness and how his work on the CircaVent project will help improve the way we understand and treat mental health issues, like bipolar disorder

Replication of patient- and sex-specific hallmarks of IBD in a human organ chip reveals stromal fibroblasts as drivers of inflammation, fibrosis, and enhanced cancer risk

Recognition highlights the growing impact of Organ Chip technology in reducing animal testing in biomedical and women’s health research

Generalizable framework for Implantable Living Materials composed of highly engineered hydrogels and synthetically engineered bacteria opens diverse novel therapeutic avenues

This collaboration will fund translational research, accelerate commercialization, and advance breakthrough healthcare innovations across multiple disciplines

Through the Wyss Institute Spark Awards, individual donors and families help advance breakthroughs that the world urgently needs

Mass General Brigham researchers combine expertise in neurology, pathology to make strides for patients with frontotemporal lobar degeneration

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Alex Li has always been fascinated by the idea of using living systems to make a positive impact. He initially pursued his interest in science, but after working at a venture capital firm… Sour…

Life-science instrumentation enables new advances in bioplastic solutions at the Wyss

New study combines tissue engineering with synthetic biology tools to grow healthy liver tissue inside the body, and lays foundation for “smart” solid organ therapies

Wyss Institute-enabled Organ Chip “avatars” will provide insights into astronaut health risks and provide a tool for future discovery of countermeasures necessary for travel to the Moon and beyond

Wyss Institute at Harvard University Endometriosis affects millions worldwide. Diagnosis can take 7 to 10 years and often relies on invasive surgery. The FemSmaht Research Team at the Wyss Institute is working to change that. We are conducting a study to develop a non-invasive method for detecting endometriosis and we are looking for menstruating individuals (endometriosis-positive and those with…

Scientists engineer a recombinase-based synthetic circuit that enables “quantitative” control of cellular differentiation and population composition By Jia LIU, Chinese Academy of Sciences Edited by Karen Pepper (BEIJING) – Cellular differentiation and a division of labor are essential to living systems as distinct cell types performing specialized functions arise in defined proportions and spati…

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Katharina Meyer is exceptionally welcoming in both her personal and professional life. At home, this takes the form of studying and improving hosting skills by experimenting with cooking and ba…

How the Wyss Institute is advancing targeted therapies, early diagnosis, and collaborative models to confront neurodegenerative disease, mental illness, and brain cancer For decades, some of the most urgent challenges in brain health have resisted progress across both academia and the pharmaceutical industry. At the Wyss Institute, we are tackling them head-on. A central focus is overcoming one o…

Through the Wyss Institute Spark Awards, individual donors and families help advance breakthroughs that the world urgently needs A one-time gel that could help stop brain cancer In contrast to advances made in other types of cancer, brain cancer survival rates remain little-changed despite years of research. Only a handful of treatments have been approved for the more than 100 types of brain tumo…

In a first-of-its-kind study, researchers demonstrate that functional nervous systems can form within self-organized living cellular robots, conferring complex movement patterns and distinct gene expression profiles By Benjamin Boettner (BOSTON) — Biobots, whose growing line of variants started with Xenobots, are fascinating tiny self-powered living robots built exclusively using frog embryonic c…

Wyss Institute’s DoriVac combined vaccine and adjuvant technology uses nanoscale precision enabled by DNA origami to induce broad immunity against infectious viruses By Benjamin Boettner (BOSTON) — The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical trial stages, the first COVID-19 mRNA vaccine was administered on 8 December 202…

Meet some of the incredible women at the Institute who are having a positive impact on the world through their work You’ve probably heard of Albert Einstein, Charles Darwin, and Thomas Edison, some of the most famous scientists and engineers who have transcended their respective fields and gained notoriety for their work. While their impact is obviously important, they only paint one specific pic…