Synthetic biology makes fateful decisions

Jessica Leff
Scientists engineer a recombinase-based synthetic circuit that enables “quantitative” control of cellular differentiation and population composition By Jia LIU, Chinese Academy of Sciences Edited by Karen Pepper (BEIJING) – Cellular differentiation and a division of labor are essential to living systems as distinct cell types performing specialized functions arise in defined proportions and spatial arrangements. A central challenge in synthetic biology has therefore been how to program cells to.