Institute for Systems Biology (ISB)

An international team of researchers has completed one of the most comprehensive longitudinal molecular studies of human diversity ever conducted, uncovering how both ethnicity and geography shape human biology at The post Global Multiomics Study Reveals How Geography and Ethnicity Shape Human Biology appeared first on Institute for Systems Biology (ISB) .

For decades, scientists have known that CD4+ T cells play a central role in orchestrating the immune system’s response to infection and cancer. But studying those cells in detail — The post A New Window Into the Immune System: ISB Researchers Develop Powerful Platform to Decode CD4+ T Cells appeared first on Institute for Systems Biology (ISB) .

Scientists at the Institute for Systems Biology (ISB) have uncovered a mechanism that may help explain how tuberculosis antibiotic resistance rapidly develops — one that begins before treatment even starts. The post How Host Stress May Prime Tuberculosis to Rapidly Gain Drug Resistance appeared first on Institute for Systems Biology (ISB) .

Scientists at the Institute for Systems Biology (ISB) have helped uncover a vast, previously hidden layer of human biology, positively identifying more than 1,700 new protein-like molecules in the human The post Scientists Uncover 1,700+ Protein-like Molecules in the ‘Dark Proteome’ appeared first on Institute for Systems Biology (ISB) .

At a recent ISB Research Roundtable, Assistant Professor Dr. Alice Kane shared new insights into one of the most fundamental questions in biology: why do some people age in good The post How the Body Ages: Exploring Frailty, Menopause, and the Biology of Healthspan appeared first on Institute for Systems Biology (ISB) .

Targeted therapy is often described as a battle against mutations. A drug hits its target, tumors shrink, and the cells that survive are the ones that happened to carry the The post The Drug That Stops Cancer Also Teaches It How to Escape appeared first on Institute for Systems Biology (ISB) .

Most cancers are defined by what they are. But some are defined by what they can become. In a new study published in Cell Reports Medicine, researchers show that a The post When Cancer Changes Identity appeared first on Institute for Systems Biology (ISB) .

Winter 2025/2026 2,800+ People Learned About ISB Science and Careers Through 5 Community Events. ISB Education joined four opportunity fairs to share ISB science and career opportunities with local communities The post 2025-26 School Year ISB Education Highlights appeared first on Institute for Systems Biology (ISB) .

Whitney Gibb used to move through life at full speed. Before COVID-19, she was active, social, and thriving in a medical device career that began in her mid-20s. She assisted The post The Hidden Toll of Long COVID: One Patient’s Story and the Search for Answers appeared first on Institute for Systems Biology (ISB) .

In the microscopic world of the human gut, bacteria are constantly under attack. Viruses called bacteriophages — or simply phages — infect bacterial cells, hijack their machinery, and burst them The post How gut bacteria survive viral attack appeared first on Institute for Systems Biology (ISB) .

Anyone who has tried probiotics or changed their diet to “feed the gut” knows the frustration: sometimes it helps, sometimes it doesn’t — and it’s rarely clear why. The same The post Will It Stick? How to Tell Whether Probiotics and Prebiotics Will ‘Take’ appeared first on Institute for Systems Biology (ISB) .

SEATTLE — ISB Professor, Director, and Senior Vice President Dr. Nitin Baliga and 62 peers have been elected to the Class of 2026 Fellows of the American Academy of Microbiology, The post Nitin Baliga Among 63 Fellows Elected to the American Academy of Microbiology appeared first on Institute for Systems Biology (ISB) .

Postdoctoral fellows are the lifeblood of research institutions, yet their contributions are often underrecognized. At the Institute for Systems Biology (ISB), postdocs enter the scientific workforce with passion, vision, and The post Behind the Breakthroughs: ISB’s Postdoctoral Fellows in Focus appeared first on Institute for Systems Biology (ISB) .

A new review co-authored by Institute for Systems Biology (ISB) scientists outlines how advances in systems biology and artificial intelligence could help detect the earliest transitions from wellness to disease, The post AI-Era Early Detection Is Shifting Healthcare from Reactive to Proactive appeared first on Institute for Systems Biology (ISB) .

In 2025, the Institute for Systems Biology marked a pivotal year — one that coincided with our 25th anniversary and underscored our enduring role in shaping the future of biomedical The post 2025 Year in Review: Breakthroughs, Milestones & Moments That Defined ISB appeared first on Institute for Systems Biology (ISB) .