obstetrics

BackgroundPreeclampsia seriously threatens maternal and infant health. Antihypertensive therapy is key to improving perinatal outcomes, yet comparative maternal-fetal evidence for oral agents remains limited.ObjectiveTo compare maternal–fetal outcomes of oral labetalol versus oral nifedipine in preeclampsia, informing individualized clinical treatment.MethodsThis retrospective cohort study includ…

Nature Medicine, Published online: 11 May 2026; doi:10.1038/s41591-026-04400-y A first-in-human trial involving selective removal of the placental protein sFlt-1 in preterm pre-eclampsia provides critical safety data, and could mark the beginning of a new era of targeted therapy for this potentially lethal pregnancy complication.

The mean body mass index (BMI) of pregnant individuals in the US is increasing. While BMIs in the National Academy of Medicine (NAM) obesity classification are associated with longer labors and higher rates of cesarean birth, the influence of BMI on the third stage of labor (TSL) and postpartum hemorrhage (PPH) is understudied. The purpose of this study was to describe the relationships: (1) betw…

Preeclampsia represents an unmasking of underlying vascular and metabolic vulnerability during the physiologic stress of pregnancy. Current first-trimester screening relies heavily on body mass index which incompletely captures qualitative metabolic dysfunction, particularly in non-obese women. In this narrative perspective, we examine the atherogenic index of plasma (AIP; log10[TG/HDL-C]), which…

A blood-filtering therapy for preeclampsia is safe for pregnant patients and their babies, according to a new pilot study.

Cedars-Sinai Health Sciences University investigators have developed and successfully tested a new treatment for pregnant women with severe early preeclampsia, a leading cause of premature birth as well as maternal and fetal death.

Nature Medicine, Published online: 27 April 2026; doi:10.1038/s41591-026-04333-6 Selective removal of the placental protein sFlt-1 via antibody-based apheresis was safe and was associated with modest reductions in blood pressure and prolongation of pregnancy in women with very preterm preeclampsia. The treatment supports conducting controlled trials to evaluate its safety and efficacy at a larger…

Cedars-Sinai Health Sciences University investigators have developed and successfully tested a new treatment for pregnant women with severe early preeclampsia, a leading cause of premature birth as well as maternal and fetal death.

This report describes a rare and complex case in which a patient, due to personal beliefs, persistently refused surgery, allowing a uterine leiomyoma to grow to 27.5 × 19.1 × 23.1 cm. This led to a series of life-threatening complications, including pseudo-Meigs syndrome (PMS) with massive pleural and ascitic effusions, 90% atelectasis of the right lung, left lower limb deep vein thrombosis (DVT)…

Uterine rupture is a rare but life-threatening obstetric emergency, with most cases occurring during late pregnancy or labor, particularly in patients with a history of uterine surgery. This report presents an exceptionally rare case of spontaneous uterine rupture at 9 weeks' gestation in a 36-year-old woman with a complex surgical history, including a midtrimester cesarean delivery for placenta …

Prof Asma Khalil, Professor of Obstetrics and Maternal Medicine at City St George’s, University of London and Consultant Obstetrician, said: “Too … read more

Kaiser Permanente study supports reassessment of one-size-fits-all approach to diagnosis and management. The post Gestational diabetes subtypes tied to distinct risks for mothers and babies appeared first on Kaiser Permanente Division of Research .

Kaiser Permanente study underscores importance of managing gestational diabetes soon after diagnosis. The post Timely blood sugar regulation in gestational diabetes is tied to less childhood obesity appeared first on Kaiser Permanente Division of Research .

A woman prepares for her first child, tracking prenatal appointments and baby registries, only to learn her blood sugar numbers have landed her in a category she never anticipated: high-risk pregnancy. She’s far from alone. Gestational diabetes now affects 79 out of every 1,000 births in the United States, and the rate has climbed without pause for nearly a decade. Northwestern Medicine researche…

"Our findings suggest timing isn't just about scheduling—it can affect how well a patient's uterus responds to labor-inducing medication."

Trial identifies possible benefits for some women, which must be balanced against potential harms from antibiotics Giving antibiotics to women within 24 hours of an obstetric tear during childbirth is associated with a reduced risk of larger/clinically relevant wound complications, find the results of a clinical trial from Denmark published by The BMJ today. The researchers say ...

New Vice President and Board Members Announced New Orleans, LA – Today Paula Amato, MD was inaugurated as President of the American Society for Reproductive Medicine (ASRM) effective October 18, 2023. Dr. Amato is a Professor of OB/GYN and REI Division Director at Oregon Health and Science University (OHSU). Dr. Amato is an oral board... Read More

Women’s health is a field all on its own in medicine, which becomes clear to students pretty early on during medical school. The physicians who specialize in women’s health—obstetrics and gynecology—are important primary care providers, but their role might seem a bit unclear. Just what is an OB/GYN? And what does an OB/GYN do each […] The post What Is an OB/GYN? Insights about doctors in gynecol…

Having a well-trained midwife at their side who can offer their assistance whatever happens is very important for expectant mothers. The Department of Obstetrics and Gynecology at Universitätsklinikum has set up a new skills and simulation lab so that trainee midwives can gain comprehensive practical skills in a clinical setting. It was opened on June […]