inflammatory-bowel-disease

IntroductionUlcerative colitis (UC) is one of the predominant forms of inflammatory bowel disease (IBD), and it is a chronic and recurring inflammation of the gastrointestinal trac. However, the therapies are associated with drug resistance and low responsiveness. Ferulic acid (FA) alleviates clinical signs and inflammatory mediators in UC, while the molecular mechanisms of FA regulation on UC re…

Northwestern Medicine investigators have identified a surprising culprit in the progression of inflammatory bowel disease, according to a study published in Nature Immunology. The post How a Common Metabolite Worsens Inflammatory Bowel Disease appeared first on News Center .

Subcutaneous delivery of an anti-TNF inhibitor therapy improved remission rates compared to placebo in patients with moderate-to-severe Crohn’s disease and ulcerative colitis who previously completed intravenous anti-TNF therapy, according to clinical trial results published in the journal Gastroenterology. The post Subcutaneous Therapy Improves Inflammatory Bowel Disease Treatment appeared first…

In a new study, researchers found a special diet holds promise for treating people with inflammatory bowel disease, or IBD. The diet is a low-calorie “fasting-mimicking” diet. The study showed the fasting-mimicking diet reduced intestinal inflammation and helped intestinal stem cells grow. With the diet, the researchers reversal of IBD pathology in mice and reduced inflammation in human patients.…

The majority of inflammatory bowel disease (IBD) consists of two related but clinically and histologically distinct conditions, ulcerative colitis and Crohn’s disease. Both conditions are characterized by chronically relapsing inflammation […]