Preventive effect of ferulic acid on dextran sulfate sodium-induced ulcerative colitis in mice

Baishuang Yin
IntroductionUlcerative colitis (UC) is one of the predominant forms of inflammatory bowel disease (IBD), and it is a chronic and recurring inflammation of the gastrointestinal trac. However, the therapies are associated with drug resistance and low responsiveness. Ferulic acid (FA) alleviates clinical signs and inflammatory mediators in UC, while the molecular mechanisms of FA regulation on UC remain elusive. The aim of this experiment is to ascertain the preventive mechanism of FA on the non-in