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Clinical trials are moving toward faster data, faster signals, and faster decisions. The FDA recently announced real-time clinical trial proof-of-concepts and a proposed pilot program designed to help trial endpoints and data signals move to the agency in real time. The agency also opened a Request for Information, with comments due by May 29, 2026. That’s a major shift for clinical development. …

Are you still recruiting for “hypertension”… or for the full cardiometabolic reality your protocol actually requires? Hypertension used to be treated (and recruited) as a single-variable disease: elevated blood pressure. That model no longer reflects clinical reality. Today’s hypertension patient is increasingly part of a broader cardiometabolic profile: obesity, insulin resistance, type 2 diabet…

Clinical trial referrals don’t usually fail because patients aren’t interested. They fail because too many patients are pushed downstream before they’re truly qualified, informed, and ready for the next step. That creates a familiar pattern across studies: high referral volume, low referral quality, overloaded site teams, delayed enrollment, and preventable screening waste that gets blamed on rec…

Obesity remains one of the most commercially important areas in clinical development, but it is also one of the easiest places to misread recruitment performance. Strong demand can make enrollment look easier than it really is. In practice, the challenge is not simply generating interest. It is identifying the right patients early, educating them clearly, and moving them forward without adding av…

Smarter Matching, Faster Access: How AI Is Changing Clinical Trial Recruitment Finding the right clinical trial has long been a frustrating and time-consuming process for patients. Many spend hours searching through listings, trying to interpret complex eligibility criteria, only to discover they don’t qualify or never hear back. That experience is starting to change. AI in clinical trial recruit…

AI in Patient Recruitment: Signal, Limits, and the Operating Reality AI is already influencing patient recruitment. The real question is whether recruitment leaders are governing it or letting it run unchecked. In our latest whitepaper, AI in Patient Recruitment: Signal, Limits, and the Operating Reality, we move beyond hype and outline a practical operating model for sponsors, CROs, and research…

An overview of key hemophilia facts The rare, inherited blood disorder hemophilia is estimated to impact approximately 20,000 individuals in the United States, and over 400,000 worldwide. Currently, there is no cure for hemophilia — but through ongoing research, medical experts are continually learning more about the disease. Though there is still a lot of information to discover regarding hemoph…

Clinical trial participants help move research forward while gaining access to the latest potential treatments. Liver disease, also known as hepatic disease, is a broad term that includes hepatitis, nonalcoholic steatohepatitis (NASH), fatty liver disease, and cirrhosis. Liver disease often develops undetected over years, without obvious symptoms. According to the American Liver Foundation, liver…

Topics: For Sponsors During the COVID-19 pandemic, many clinical trials adapted by adding virtual elements to their traditional trial approaches. While many could not go fully virtual due to the need to collect samples at specific milestones and check on patients in person, folding in technology kept patients safer and reduced the burden to participation. In many cases, it allowed research to sta…

What to know about colon cancer stages Despite the fact that colorectal cancer cases have been declining in the United States since the mid-1980s, it is still the third most common cancer diagnosed each year excluding skin cancer. Often shortened to colon cancer, colorectal cancer occurs when cells in the colon and/or the rectum begin to grow uncontrollably and eventually spread to other parts of…

Clinical trial participants help move research forward while gaining access to the latest potential treatments. Obesity is defined as having a body mass index (BMI) of 30 or more, and according to the CDC, about 35% of American adults and 17% of American children and teenagers fall into this category. People who are obese are at higher risk of health problems such as type 2 diabetes, heart diseas…

Does Emotion-Based Marketing Work for Clinical Trial Patient Recruitment? Patients are more likely to take action for their health after seeing ads that trigger fear and hope, according to new research in the 2018 Wunderman Health Inertia Study. While healthcare marketers typically jump at the chance to test out new research findings with their own audience, those who communicate clinical trial o…

How to achieve patient centricity in clinical trial listings Facilitating medical research relies on patient participation, yet research protocols often overlook the patient perspective. Improving patient centricity in clinical trials demands prioritizing the patient experience. To better understand what patients want and need at the beginning of their clinical trial journey, Antidote conducted a…

The top patient retention strategies in clinical trials Clinical trial recruitment is a significant challenge for sponsors as insufficient patient enrollment can account for delays in up to 80% of all studies. However, even when these studies successfully reach their randomization targets, clinical trial managers must turn their focus on retaining these participants. Data indicates that the dropo…

Delivering on Diversity: Tuskegee and what it means for minority participation in medical research today Every conversation about minority participation in medical research inevitably winds up with the “T” word – Tuskegee. Though the Tuskegee Syphilis Experiment is largely cited as the driver of low minority participation in medical research, recent studies show minorities are more willing than t…

Topics: For Patients Jessica Thomas was driving one day when she realized she was having problems with her vision. Over the next couple of weeks, she began experiencing some unexplained numbness, tingling, and cognitive issues. “I had trouble coming up with words, which was super frustrating, as I was in graduate school at the time,” says Jessica. Within a couple of months from the onset of that …

3 ways patient-centric recruitment can make all the difference Patient-centricity is at the heart of the clinical research community. It’s a guiding principle for study design and recruitment efforts that puts the focus on the people at the core of research: volunteers and their loved ones. At Antidote, we think of patient-centricity as letting the patient voice drive how we think about the recru…

How to Run Effective Clinical Trial Advertising Tests In clinical trial advertising, running tests to find your most successful ads is one of the best ways to improve your campaigns. But it's also easy to set up tests incorrectly and skew your results. Follow these tips to create effective tests that give you valuable information about the best way to reach your audience. Step 1: Choose one facto…

How to Optimize Patient Recruitment in Five Steps Of all of the elements of a clinical trial, optimizing patient recruitment may make the most significant impact on trial timelines. Even if you're meeting your recruitment goals – a rare accomplishment, to say the least – trials and budgets always benefit from better efficiency. To optimize patient recruitment, it helps to keep a close eye on how …

This Clinical Trials Day, Share Why You Support Medical Research Happy Clinical Trials Day! Here at Antidote, today is an opportunity to talk about why medical research matters – and to celebrate the volunteers who make it possible. New treatments simply can't reach patients without the support of clinical trial volunteers. Millions of patients volunteer for research every year, and help make bet…