How a Well-Intentioned Enrollment Fix Made the Underlying Problem Worse

Adding sites is the fastest lever when enrollment stalls. Here is why it fails, and what to run first. When enrollment falls behind, expanding the network of clinical research sites is the lever sponsors can pull fastest. Site counts are visible, contractable, and reportable to leadership. The reflex makes sense. The real question is whether the market holds enough patients who can qualify, and most site plans assume the answer instead of testing it.