BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is frequently followed by persistent cognitive impairment, characterized by a complex and multifactorial pathological mechanism. While the role of the “microbiota-gut-brain axis” in neurocognition has garnered increasing attention, the specific ways in which gut microbiota and their derived metabolites might be associated with the development an…
Nature Microbiology, Published online: 29 July 2026; doi:10.1038/s41564-026-02434-z Lipidomics and proteomics in mice colonized with variable gut microbiota reveal an important role of gut microbes in restricting lipid uptake via triggering Myd88 signalling and the degradation of phosphatidylcholine in bile.
Autism spectrum disorder (ASD) is a common neurodevelopmental condition frequently accompanied by gastrointestinal symptoms, pointing to a potential role of the gut microbiota–brain axis. To explore this connection, the present review synthesizes findings from studies published between 2016 and 2026, including observational studies, meta-analyses, animal experiments, and clinical trials, with the…
PurposeThe global crisis of antimicrobial resistance has reached critical levels, with multi-drug resistant (MDR) bacterial pathogens threatening to render conventional antibiotics ineffective. This mini review synthesizes recent evidence from 2020 to 2026 on bacteriophage therapy against MDR bacteria, examining clinical applications, engineering advances, mechanistic insights, and emerging techn…
IntroductionThe study evaluates the preventive effects of Polygonatum sibiricum and Poria cocos (3:1) on spleen deficiency constipation in mice, focusing on the brain-gut axis, gut microbiota, and oxidative stress. The findings aim to inform the prevention and treatment of this condition.MethodsThirty male specific pathogen-free (SPF) KM mice (4 weeks old, 20 ± 2 g) were randomized into a normal …
