constipation

Frontiers in Pharmacology | New and Recent Articles

IntroductionThe study evaluates the preventive effects of Polygonatum sibiricum and Poria cocos (3:1) on spleen deficiency constipation in mice, focusing on the brain-gut axis, gut microbiota, and oxidative stress. The findings aim to inform the prevention and treatment of this condition.MethodsThirty male specific pathogen-free (SPF) KM mice (4 weeks old, 20 ± 2 g) were randomized into a normal …

biologybrain-gut-axisconstipationgut-microbiota