guidetopharmacology blog

Version 2026.1 of the IUPHAR/BPS Guide to Pharmacology database was released on 12th March 2026, our first database release of the year. This blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,127 human targets, 1,807 of which have curated quantitative ligand interactions. - 13,721 ligands, 9,895 of which have curated quantitative target interactions.…

The Guide to Pharmacology have been collaborating with AntibioticDB (https://www.antibioticdb.com; ADB) since 2019, with the aim of extending the coverage of antibacterial compounds in GtoPdb and providing comprehensive chemistry and pharmacology for selected antibacterials curated with ADB. The collaboration has been supported more recently by the Global Antibiotic Research and Development Partn…

Why is IUPHAR/BPS Guide to Pharmacology asking for access fees? The IUPHAR/BPS Guide to Pharmacology (GtoPdb) has always been an open-access, freely available resource. Our expert-curated database of pharmacological data has been maintained over the past 10-15 years on ever changing and sadly, diminishing financial resources. We really want to keep GtoPdb open-access for all, but maintaining and …

The Concise Guide to Pharmacology 2025/26 was published on 29 December 2025 and marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. The Concise Guide acts as a substantially condensed version of the more detailed information and links available on the IUPHAR/BPS Guide to Pharmacology website, and serves as a permanent, citable, point-in-time r…

Version 2025.4 of the IUPHAR/BPS Guide to Pharmacology database was released on 10th December 2025, our fourth and final release of the year. This blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,118 human targets, 1,797 of which have curated quantitative ligand interactions. - 13,591 ligands, 9,816 of which have curated quantitative target interact…

Version 2025.3 of the IUPHAR/BPS Guide to Pharmacology database was released on 10th September 2025, our second release of the year. This blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,112 human targets, 1,790 of which have curated quantitative ligand interactions. - 13,503 ligands, 9,758 of which have curated quantitative target interactions. - 2…

Why is IUPHAR/BPS Guide to Pharmacology asking for access fees? The IUPHAR/BPS Guide to Pharmacology (GtoPdb) has always been an open-access, freely available resource. Our expert-curated database of pharmacological data has been maintained over the past 10-15 years on ever changing and sadly, diminishing financial resources. We really want to keep GtoPdb open-access for all, but maintaining and …

Version 2025.2 of the IUPHAR/BPS Guide to Pharmacology database was released on 18th June 2025, our second release of the year. This blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,103 human targets, 1,767 of which have curated quantitative ligand interactions. - 13,254 ligands, 9,568 of which have curated quantitative target interactions. - 2,119 …

In the last academic year (September 24 – April 25) we supported two undergraduate, final-year projects (Honours Projects) that looked into uses of ‘artificial intelligence’ tools to improve access to or capabilities of the Guide to Pharmacology. Both projects focussed on the uses of Large Language Models (LLMs) (such as OpenAI’s ChatGPT) to translate natural language queries to Structured Query …

Our latest database report provides an overview of progress and status of the IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) for the period November 2024 to April 2025. It can also be access at our Zenodo repository https://doi.org/10.5281/zenodo.15342610

The latest release (version 2025.1) of the IUPHAR/BPS Guide to Pharmacology database has been made. Released on 2nd April 2025 this is the first release of the year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,097 human targets, 1,758 of which have curated quantitative ligand interactions. - 13,131 ligands, 9,485 of which have cur…

The latest release (version 2024.4) of the IUPHAR/BPS Guide to Pharmacology database has been made. Released on 4th December 2024 this is the fourth release of the year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,089 human targets, 1,750 of which have curated quantitative ligand interactions. - 12,950 ligands, 9,392 of which have…

Our latest database report provides an overview of progress and status of the IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) for the period April 2024 to October 2024. It can also be access at our Zenodo repository https://doi.org/10.5281/zenodo.14046004 Our latest database report provides an overview of progress and status of the IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) for the period April 2024 to …

The latest release (version 2024.3) of the IUPHAR/BPS Guide to Pharmacology database has been made. Released on 3rd October 2024 this is the third release of the year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,086 human targets, 1,747 of which have curated quantitative ligand interactions. - 12,862 ligands, 9,356 of which have c…

The latest release (version 2024.2) of the IUPHAR/BPS Guide to Pharmacology database has been made. Released on 26th June 2024 this is the second release of the year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,083 human targets, 1,744 of which have curated quantitative ligand interactions. - 12,730 ligands, 9,292 of which have cu…

A new release, version 2024.1, has been made of the IUPHAR/BPS Guide to Pharmacology database. Released on 26th March 2024 this is the first release of the year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,067 human targets, 1,732 of which have curated quantitative ligand interactions. - 12,590 ligands, 9,204 of which have curated…

The essential guide for those working in the vital search for new drugs A FREE education and research resource What’s in it for you? Published as a special issue in the British journal of Pharmacology every 2 years, The Concise Guide to PHARMACOLOGY provides brief overviews of the key properties of over 1,800 human drug targets and their pharmacology, and is a view of the data in the IUPHAR/BPS G…

The IUPHAR/BPS Guide to Pharmacology is delighted to be named as one of 15 new Global Core Biodata Resources (GCBRs) by the Global Biodata Coalition (GBC). The GBC announced the outcome of its 2023 selection round for GCBRs on 11th December 2023 – you can read about the announcement here. GtoPdb is proud to meet the stringent eligibility criteria that were part of the selection process. This cove…

The latest release of the IUPHAR/BPS Guide to Pharmacology database was made on 29th November 2023. This database release is version 2023.3, and is the third release this year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,056 human targets, 1,715 of which have curated quantitative ligand interactions. - 12,344 ligands, 9,072 of whi…

The latest release of the IUPHAR/BPS Guide to Pharmacology database was made on 7th August 2023. This database release is version 2023.2, and is the second release this year. The following blog post gives details of the key content updates and website changes. GtoPdb now contains: - 3,039 human targets, 1,695 of which have curated quantitative ligand interactions. - 12,163 ligands, 8,959 of which…