Database Release 2025.4
guidetopharmacology
Version 2025.4 of the IUPHAR/BPS Guide to Pharmacology database was released on 10th December 2025, our fourth and final release of the year. This blog post gives details of the key content updates and website changes. GtoPdb now contains:
- 3,118 human targets, 1,797 of which have curated quantitative ligand interactions.
- 13,591 ligands, 9,816 of which have curated quantitative target interactions.
- 2,156 approved drugs, 1,212 with curated quantitative interactions.
- Clinical use summaries.