Institute of Structural Biology

Tabea C. Fricke, Ruth A. Pumroy, Julia A. Rocereta, José J. De Jesús-Pérez, George Oprita, Marvin J. A. Meyer, Christine Herzog, Frank G. Echtermeyer, Kerstin Hill, Andreas Leffler & Vera Y. Moiseenkova-Bell Nature Communications   Abstract Transient receptor potential vanilloid 2 (TRPV2) is a broadly expressed ion channel implicated in diverse physiological and pathological processes. … Continue…

Congratulations to Kushol Gupta’s lab for their latest publication in Advanced Materials. Lipid Nanoparticle Co-Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy Marshall S. Padilla,  Jacqueline J. Li,  Qunzhou Zhang,  Korey Patwari,  Shihong Shi,  Hannah M. Yamagata,  Ryann A. Joseph,  Briyanna N. Hymms,  Sridatta V. Teerdhala,  Emily Fitzgerald,  Ori Z. Chalom,…

Welcome back to another academic year of Structural Biology Talks!

Please join us on September 4th,2025 at 2Pm for our monthly Mass Spectrometry Interest Group Meeting. Grace Park (James Petersson) and Yang Liu (Dr. Audrey Odom John Lab) will be presenting. Contact Camila Spaulonci to register. email: camila.spaulonci@pennmedicine.upenn.edu

Come and visit us on September 11. Table 25 with live presentation at 11:30AM. Check the schedule here.        

Palumbos SD, Popolow J, Goldsmith J, Holzbaur ELF. Autophagic stress activates distinct compensatory secretory pathways in neurons. Proc Natl Acad Sci U S A. 2025 Jul 15;122(28):e2421886122. doi: 10.1073/pnas.2421886122. Epub 2025 Jul 7. PMID: 40623183.

Authors: Yi-Wei Chang, Shrawan Kumar Mageswaran, Biao Zuo. Egan MS, O’Rourke EA, Mageswaran SK, Zuo B, Martynyuk I, Demissie T, Hunter EN, Bass AR, Chang YW, Brodsky IE, Shin S. Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages. Elife. 2025 Mar 27;12:RP90107. doi: 10.7554/eLife.90107. PMID: 40162563; PMCID: PMC11957546. Abstract Salmonella enterica serovar…

🎉 Congratulations to Drs. Lynch, Burslem, Marmorstein, Yi-Wei, and the entire research team on the publication of your latest research article in the newest issue of Science magazine! 🧬📖   Read the full article here: https://www.science.org/doi/10.1126/science.adq7597

🔬 The 4th Structural Biology Symposium is almost here!Don’t miss out—there’s still time to register.Secure your spot by clicking the link below! 4th Structural Biology Symposium Registration and Abstract Submission.