drug-repurposing

Delve into the hidden innovation system of drug repurposing. When patents expire and commercial value fades, a new wave of research starts. The post The hidden innovation system behind drug repurposing appeared first on Labiotech.eu . © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is…

BackgroundPyruvate kinase liver and red blood cells (PKLR) is linked to metabolic dysfunction-associated steatotic liver disease (MASLD). Previous study, we identified JNK-IN-5A, a c-Jun N-terminal kinase (JNK) inhibitor that suppresses PKL expression in HepG2 cells using computational drug repurposing and screened out four hit JNK-IN-5A derivatives (SET-151, SET-152, SET-162, SET-130).Materials …

At Centre for Brain and Mind. This project aims to develop a systematic strategy to discover and repurpose drugs for psychiatric …