Microsystems & Nanoengineering
A high-throughput modular microfluidic platform for versatile functional assays at single-cell level
Abstract Investigating astrocyte–neuron communication in the absence of neuron-to-neuron signalling is challenging using traditional culture systems due to the complexity of synaptic networks. To address this, we designed a three-compartment microfluidic co-culture device that fluidically isolates two neuronal populations while permitting astrocyte growth throughout. This design enables assessmen…
Abstract The detection and interpretation of brain signals are crucial for advancing brain-computer interface (BCI) technologies. Local field potential (LFP) signals, reflecting synchronized neuronal ensemble activity, offer insights into coordinated neural function. In this study, we present a miniaturized tunneling magnetoresistance (TMR)-based neural magnetrode optimized for in vivo LFP magnet…
Abstract A new synthetic strategy and associated mechanism have been developed, in which two carrier conduction channels of n- and p-type semiconductors on the surface of one material are automatically and advantageously selected during surface reactivity. The key step is to uniformly channel non-equilibrium metal oxides of CuO x and SnO x throughout the sample by applying a flame chemical vapour…
Abstract To address the demand for flow-induced vibration monitoring of steam generator heat transfer tubes in pressurized water reactors under high-temperature (350 °C) and high-pressure (17.5 MPa) conditions, a fiber-optic Fabry–Pérot interferometric accelerometer based on a composite Fabry–Pérot cavity structure is proposed. The sensor employs a symmetrically arranged multidirectional cantilev…
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