Retrospective longitudinal analysis of blood microRNA-7-5p as a possible progression biomarker in people with Parkinson’s disease
Christopher Adams
BackgroundMicroRNA-7-5p (miR-7-5p) may play a neuroprotective role in people with Parkinson’s disease (PwP), as it has been found to regulate α-synuclein (α-syn) and the NLRP3 inflammasome in animal models of Parkinson’s disease (PD).ObjectiveThe study aimed to investigate the use of miR-7-5p as a potential biomarker for disease progression in PwP by correlating it with time, clinical measures, and neurofilament light chain (NfL).MethodsWe performed a longitudinal retrospective analysis of blood