The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten
Sankar Ghosh
Nature Immunology, Published online: 30 April 2026; doi:10.1038/s41590-026-02506-6 Ghosh and colleagues examine the mechanism underlying the long-noncoding RNA lnc13-mediated regulation to gluten tolerance. The authors show lnc13 restrains CD8αβ+ inter-epithelial lymphocyte responsiveness to IL-15 signaling.