Foamy microglia link oxylipins to disease progression in multiple sclerosis
Mario van der Stelt
Nature Neuroscience, Published online: 21 May 2026; doi:10.1038/s41593-026-02302-3 Foamy microglia are associated with multiple sclerosis progression, linking phagocytosis, altered lipid metabolism (oxylipins) and lysosomal stress to nonclassical neuroinflammation and disease severity, highlighting potential therapeutic targets.