Deep phenotyping of skin tissue remodeling in patients with systemic sclerosis treated with CD19-CAR T cells
Christina Bergmann
Nature Communications, Published online: 23 May 2026; doi:10.1038/s41467-026-72817-7 CD19-specific chimaeric antigen receptor (CAR) T cell therapy has recently been evaluated for the treatment of systemic sclerosis (SSc). Here, the authors use multiomic analyses to demonstrate that CD19 CAR T cell treatment promotes skin tissue remodeling in patients with SSc.