Combination therapy with broadly neutralizing antibodies, antiretroviral therapy and CCR5 blockade limits viral reservoir seeding in infant macaque model of HIV

Nature Microbiology, Published online: 10 August 2026; doi:10.1038/s41564-026-02444-x A combined therapy using broadly neutralizing antibodies that target the HIV envelope protein, the CCR5-blocking antibody leronlimab and antiretroviral therapy limits seeding of the viral reservoir in an infant macaque model of HIV at 72 h post-infection.