Eco-friendly synthesis of an antimicrobial polymer (1,4-bis(methacryloyl)piperazine) via maghnite catalysis: in vitro activity and in silico drug-likeness
Ahmed Barhoum
BackgroundPoly (1,4-bis(methacryloyl)piperazine) (poly (NBMP)) is a piperazine-based polymer with potential biomedical applications. Green clay catalysts, maghnite-H+ and maghnite-Na+; offer an eco-friendly approach for monomer (NBMP) and polymer (poly (NBMP)) synthesis with improved yields and low toxicity.AimTo synthesize poly (NBMP) via green catalysis, evaluate its structural properties, and investigate its antimicrobial potential along with drug-likeness and molecular interaction profiles o