Impact of Coffee and Atorvastatin on Atherogenic Index of Plasma and Kidney Function in Hyperlipidemic Rats

The present study was conducted to investigate the effects of decaffeinated and caffeinated coffee consumption, in a combination with atorvastatin, on selected lipidemic profle parametes, as well as liver and kidney function biomarkers in hyperlipidemia-induced rats. Major coffee constituents, including caffeine and chlorogenic acid, were extracted and quantified using HPLC-DAD. A total of 54 female Wistar rats were allocated into three main experimental groups: a standard diet group (SD), a hi