Polymer–mRNA complexes for monocyte-trafficked, lymph node-targeted cancer vaccination
Zhiyuan Zhong
Nature Biomedical Engineering, Published online: 05 May 2026; doi:10.1038/s41551-026-01672-0 A transferrin receptor-associating polyplex formed by complexing mRNA with modified polyethylenimine enables monocyte trafficking and lymph node targeting for potent and selective cancer vaccination.