ferroptosis

BackgroundMetabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) has emerged as one of the major chronic liver diseases worldwide, and its progression mechanisms have not yet been fully elucidated. Ferroptosis is a form of programmed cell death driven by iron-dependent lipid peroxidation. In recent years, it has been demonstrated to play a crucial regulatory role in the progression of M…

Human papillomavirus (HPV)-positive cervical cancer develops under persistent metabolic, replicative, and oxidative stress and frequently exhibits limited sensitivity or acquired resistance to cisplatin-based concurrent chemoradiotherapy (CCRT). In this context, ferroptosis represents a potential therapeutic vulnerability, yet the regulatory networks that sustain ferroptosis resistance in HPV-pos…