Glioma, especially glioblastoma multiforme (GBM), has become one of the major clinical challenges in the field of neurooncology due to its high invasiveness and significant multidrug resistance (MDR). The mechanism of drug resistance is complex and involves the synergy of many factors, including the overexpression of MDR related transporters such as P-glycoprotein (P-gp), multidrug resistance ass…
A study by the University of Barcelona has discovered why the two main types of lung cancer — adenocarcinoma of the lung and squamous cell carcinoma — respond differently to anti-angiogenic therapy, that is, drugs that block the formation of new blood vessels that tumors need in order to grow.
One of the greatest challenges in cancer treatment is drug resistance. A treatment may work well at first, shrinking tumors and slowing disease progression, but over time cancer cells can adapt and learn how to survive. This problem is especially common in advanced kidney cancer, where many patients eventually run out of effective treatment options. […] The post New Therapy May Beat Drug Resistan…
Nearly half of all adults in the United States live with hypertension, and for roughly one in ten of them, conventional drug treatments simply don’t work. A research team at Pennsylvania State University (PSU) has developed a potential answer: a soft, 3D printed bioelectronic device that attaches directly to one of the body’s most critical…
