Biosensors and Bioelectronics

We report a rapid test strip based on mesoporous silica nanoparticles functionalized with a specific GABA<sub>B</sub> receptor agonist to selectively detect γ-hydroxybutyric acid (GHB) in urine samples. The sensing mechanism involves rhodamine B-loaded MCM-41 silica nanoparticles whose pores are capped with a GABA-derived ligand (baclofen) acting as a gatekeeper via supramolecular interactions wi…

Forensic Toxicology and Drug AnalysisLife SciencesPharmacology, Toxicology and PharmaceuticsToxicology
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