Efficacy, effectiveness and safety of psoriasis treatment in diabetic and hypertensive elderly patients: Clinical, biochemical, and hematological outcomes, a prospective non-randomized controlled interventional study

Psoriasis is a type of epidermal, hereditary, immune-mediated inflammatory disorder that is often connected to metabolic comorbidities especially in the elderly. Methotrexate is administered once weekly in moderate or severe psoriasis, in addition to anti-glucose effects, Metformin has anti-inflammatory and metabolic effects that can be beneficial in improving the results of treating psoriasis. The purpose of this study was to assess the efficacy, effectiveness and safety of methotrexate treatme