Zhao et al. accelerate antimicrobial polymer design with a novel database and machine learning. Drug-resistant microorganisms pose increasing pressure on healthcare systems, underscoring the urgent need for effective disinfectants. In this vein, antimicrobial polymers (AMPs) offer a promising solution by inhibiting or eradicating microbes through diverse mechanisms without fostering resistance. With low toxicity and enhanced durability, AMPs are strong candidates for next-generation...