Nature Immunology, Published online: 14 August 2026; doi:10.1038/s41590-026-02606-3 Belz and colleagues show that Peyer’s patch M cells are required for ILC3 localization, proliferation and IL-22 production within the dome epithelium.
Peyer’s patch M cells organize an epithelial niche that sustains group 3 innate lymphoid cells and IL-22
Gabrielle T. Belz

