Abstract. Cerebrovascular disease (CVD) is a major medical problem, significantly impacting patients' quality of life and social adaptation [1]. Asthenia and affective disorders are the most common consequences of both acute cerebrovascular diseases, such as stroke and transient ischemic attacks, and chronic ones [2]. Purpose: To assess and compare the level of asthenia, the severity of affective disorders (anxiety and depression), and the quality-of-life indicators in patients with chronic cerebral circulatory insufficiency (CCCI), depending on the presence or absence of a history of acute cerebrovascular accident (CVA).Material and methods. A review of literary sources in Russian and English was conducted, the RSCI and PubMed databases were used. The clinical study included 54 patients with a diagnosis of chronic cerebrovascular insufficiency, 40 women (74.1%), 14 men (25.9%), average age 64.43±7.28 years. Patients were divided into 2 groups: the first group (n=28) included patients with a history of acute cerebrovascular insufficiency (ischemic stroke), including 19 women (67.9%), 9 men (32.1%), average age 63.14±7.25 years, the second group (n=26) - patients without a history of acute cerebrovascular insufficiency (women - 21 (80.8%), men - 5 (19.2%), average age 65.81±7.18 years).
