Predicting ordinal clinical outcomes in at-risk mental states: a multimodal approach

IntroductionClinical outcomes in individuals with at-risk mental states (ARMS) are heterogeneous and extend beyond the simple dichotomy between transition and non-transition to psychosis. While previous studies have primarily focused on predicting the transition to psychosis, few have systematically examined multiple outcome stages, including remission and persistent subthreshold symptoms, using integrated neurobiological markers. This study aimed to identify the predictors of multilevel clinica