Shedding light on the undiscovered pathways of yeast metabolism
Steve Mathew D A
Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01529-4 What if substantial biochemical information remains absent from current genome-scale metabolic models? By merging retrobiosynthesis with deep learning, Yeast-MetaTwin uncovers promiscuous reactions and predicts degradation routes with tangible engineering consequences.