Nature Catalysis

Nature Catalysis, Published online: 30 April 2026; doi:10.1038/s41929-026-01545-4 Author Correction: Peaks and pitfalls of electrocatalytic CO 2 reduction descriptor models

Nature Catalysis, Published online: 29 April 2026; doi:10.1038/s41929-026-01532-9 Stereoselective radical C–C couplings remain a major challenge. Now photometallobiocatalytic cross-coupling of organotrifluoroborates and α-diazoesters is achieved with high enantio- and diastereoselectivity via an outer-sphere radical mechanism mediated by engineered cytochrome c and eosin B.

Nature Catalysis, Published online: 29 April 2026; doi:10.1038/s41929-026-01531-w Pt-based alloy clusters within zeolite channels are promising catalysts for the dehydrogenation of alkanes, but controlling their distribution under operation is challenging. Now a water-soaking treatment to regenerate and minimize atom migration in K–PtSn@MFI catalysts is introduced, resulting in enhanced stability…

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01528-5 Stereocontrol over radical intermediates is highly sought after in asymmetric organic synthesis, yet current approaches remain limited and difficult to generalize. A photobiocatalytic strategy employing thiamine diphosphate (ThDP)‑dependent enzymes now achieves simultaneous and precise control over two prochiral rad…

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01534-7 Supramolecular control of cationic intermediates

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01529-4 What if substantial biochemical information remains absent from current genome-scale metabolic models? By merging retrobiosynthesis with deep learning, Yeast-MetaTwin uncovers promiscuous reactions and predicts degradation routes with tangible engineering consequences.

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01520-z The hydrogenation of pyridine molecules to their corresponding piperidines remains a particularly challenging transformation. Now, a class of catalytic materials based on the encapsulation of metal nanoparticles within zeolite frameworks has emerged as a promising solution to this challenge.

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01530-x Understanding the charge transfer at microbe–semiconductor interfaces in biohybrids is valuable for advancing solar-to-chemical conversion. Now, the reverse electron transfer in Shewanella–haematite hybrids is quantified using multimodal single-particle imaging, revealing facet-dependent efficiency.

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01527-6 Conventional catalyst design guided by thermodynamic descriptors often falls short in solid-phase electrochemical conversion reactions. A study now establishes an electronic property criterion for dual-atom catalysts, revealing that matching orbital symmetry can induce solid-phase metallization to enable continuous …

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01537-4 Splitting water under dryness

Nature Catalysis, Published online: 28 April 2026; doi:10.1038/s41929-026-01536-5 Zeolites like to move it

Nature Catalysis, Published online: 16 April 2026; doi:10.1038/s41929-026-01533-8 Direct electroreduction of CO2 to produce high-concentration formate is challenged by the low flux of liquids in typical catholyte-free membrane electrode assemblies (MEAs). Now, a high-flux MEA using core–shell Cu/Bi nanowires grown on three-dimensional Cu foam as the cathode enables CO2 electroreduction to high-co…

Nature Catalysis, Published online: 15 April 2026; doi:10.1038/s41929-026-01525-8 Conversion-type batteries involving solid–solid transformations can store more energy than intercalation materials; however, their rates and cyclability have been limited by kinetics and incomplete conversion. This study introduces homonuclear dual-atom catalysts that increase the conductivity of insulating solid in…

Nature Catalysis, Published online: 13 April 2026; doi:10.1038/s41929-026-01522-x Catalytic access to axially chiral diaryl ethers remains limited by the difficulty of enantioselective C–O bond formation. Now peptide-mimic phosphonium salts enable atroposelective nucleophilic aromatic substitution-driven C–O bond construction, affording axially enantioenriched diaryl ethers.

Nature Catalysis, Published online: 13 April 2026; doi:10.1038/s41929-026-01526-7 Descriptors have been used to predict product selectivity in electrocatalytic CO2 reduction on metals. This Analysis confirms that CO adsorption energy is suitable for predicting CO, but the work function is also needed to predict HCOO− and H2 selectivity. By contrast, the mechanism for C–C coupled products is too c…

Abstract Hydrogenation of pyridines is particularly challenging because their strong coordination to metal sites hinders hydrogen adsorption and can poison the catalysts. Here we show that Ni nanoparticles (NPs) within zeolite crystals can overcome this problem, owing to a network of micropores that features a greater proportion of free Ni sites for hydrogen adsorption even in the presence of pyr…

Abstract A systematic understanding of cellular metabolism is essential for engineering yeast and uncovering the principles of metabolic robustness and evolution, yet much of its metabolic space remains unexplored. Although yeast genome-scale metabolic models have been reconstructed and curated for over two decades, more than 90% of the yeast metabolome remains uncovered. Here, to address this ga…

Abstract The direct electroreduction of CO2 at an electrolyte-free cathode to generate liquid chemical products with high concentration, selectivity and stability is highly desired, yet extremely challenging, and such systems are lacking. Here we report a high-flux membrane electrode assembly design that uses core–shell structural Cu/Bi nanowires grown on three-dimensional Cu foam with a mean por…

Abstract Radical C(sp3)–C(sp3) bond formation has emerged as a promising strategy for constructing molecules rich in C(sp3)–stereocentres. However, achieving chemo- and enantioselective recombination of two prochiral alkyl radicals remains a substantial challenge. Here we synergistically repurpose a thiamine-dependent benzoylformate decarboxylase (PpBFD) with a photoinduced radical process, unloc…