Key points

  • GLP-1 drugs are widely known for their weight-loss effects, but they may also have antidepressant properties.
  • When tested on mice in a recent study, GLP-1 drugs led to weight loss and reversed depression-like behavior.
  • The effect disappeared in germ-free mice, indicating that gut microbes play a key role.
  • The effect was found to be dependent on a particular microbe that produces end