Efficacy and safety of desvenlafaxine in treating patients with major depressive disorder: a network meta-analysis
Chenzhao Yuan
Background and objectiveDesvenlafaxine (DVS), a commonly used serotonin-norepinephrine reuptake inhibitor (SNRI), is widely applied in the treatment of major depressive disorder (MDD). However, the efficacy and safety of different DVS dosages remain controversial. This study aims to systematically evaluate the efficacy and safety of various doses of DVS in treating MDD, providing evidence-based guidance for clinical dose selection.MethodsA systematic search was conducted in PubMed, Embase, Web o